EC Number | Application | Comment | Organism |
---|---|---|---|
2.7.7.48 | medicine | NS5B is strictly required for viral replication and thus represents an attractive therapeutic target | Hepacivirus C |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.7.7.48 | Fructus Ligustri Lucidi aqueous extract | 0.005 mg/ml, inhibits intracellular NS5B-catalyzed RNA synthesis | Hepacivirus C |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.7.7.48 | Hepacivirus C | - |
HepG2, Hep3B, and Bel-7402 cells transfected with | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.7.48 | nucleoside triphosphate + RNAn | - |
Hepacivirus C | diphosphate + RNAn+1 | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.7.7.48 | NS5B | - |
Hepacivirus C |
2.7.7.48 | RDRP | - |
Hepacivirus C |
2.7.7.48 | RNA-dependent RNA polymerase | - |
Hepacivirus C |