BRENDA - Enzyme Database

Tea flavanols inhibit cell growth and DNA topoisomerase II activity and induce endoreduplication in cultured Chinese hamster cells

Neukam, K.; Pastor, N.; Cortes, F.; Mutat. Res. 654, 8-12 (2008)

Data extracted from this reference:

Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
5.6.2.2
(+)-catechin
-
Cricetulus griseus
5.6.2.2
(-)-epicatechin
-
Cricetulus griseus
5.6.2.2
(-)-epigallocatechin
-
Cricetulus griseus
5.6.2.2
(-)-epigallocatechin-3-gallate
-
Cricetulus griseus
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
5.6.2.2
Cricetulus griseus
-
-
-
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
5.6.2.2
CHO-AA8 cell
-
Cricetulus griseus
-
5.6.2.2
ovary
-
Cricetulus griseus
-
Cofactor
EC Number
Cofactor
Commentary
Organism
Structure
5.6.2.2
ATP
-
Cricetulus griseus
IC50 Value
EC Number
IC50 Value
IC50 Value Maximum
Commentary
Organism
Inhibitor
Structure
5.6.2.2
0.0372
-
-
Cricetulus griseus
(-)-epicatechin
5.6.2.2
0.046
-
-
Cricetulus griseus
(+)-catechin
5.6.2.2
3.61
-
-
Cricetulus griseus
(-)-epigallocatechin
5.6.2.2
3.78
-
-
Cricetulus griseus
(-)-epigallocatechin-3-gallate
Cofactor (protein specific)
EC Number
Cofactor
Commentary
Organism
Structure
5.6.2.2
ATP
-
Cricetulus griseus
IC50 Value (protein specific)
EC Number
IC50 Value
IC50 Value Maximum
Commentary
Organism
Inhibitor
Structure
5.6.2.2
0.0372
-
-
Cricetulus griseus
(-)-epicatechin
5.6.2.2
0.046
-
-
Cricetulus griseus
(+)-catechin
5.6.2.2
3.61
-
-
Cricetulus griseus
(-)-epigallocatechin
5.6.2.2
3.78
-
-
Cricetulus griseus
(-)-epigallocatechin-3-gallate
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
5.6.2.2
(+)-catechin
-
Cricetulus griseus
5.6.2.2
(-)-epicatechin
-
Cricetulus griseus
5.6.2.2
(-)-epigallocatechin
-
Cricetulus griseus
5.6.2.2
(-)-epigallocatechin-3-gallate
-
Cricetulus griseus
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
5.6.2.2
CHO-AA8 cell
-
Cricetulus griseus
-
5.6.2.2
ovary
-
Cricetulus griseus
-