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Literature summary extracted from

  • Cook, T.; Roos, D.; Morada, M.; Zhu, G.; Keithly, J.S.; Feagin, J.E.; Wu, G.; Yarlett, N.
    Divergent polyamine metabolism in the Apicomplexa (2007), Microbiology, 153, 1123-1130.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.2.2 ADP + carbamoyl phosphate Toxoplasma gondii The parasite actively transports arginine and ornithine, which are converted via the arginine dihydrolase pathway to citrulline and carbamoyl phosphate, resulting in the formation of ATP via carbamate kinase ATP + NH3 + CO2
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 ?
2.7.2.2 ADP + carbamoyl phosphate Toxoplasma gondii RH The parasite actively transports arginine and ornithine, which are converted via the arginine dihydrolase pathway to citrulline and carbamoyl phosphate, resulting in the formation of ATP via carbamate kinase ATP + NH3 + CO2
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 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.2.2 Toxoplasma gondii
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2.7.2.2 Toxoplasma gondii RH
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Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.7.2.2 980
-
 carbamate kinase is determined in incubations containing 1 mM ADP, 20 mM MgSO4, 0.15 mM luciferin, 1 mg firefly lantern extract, and 1 mM carbamoyl phosphate, in 50 mM potassium phosphate buffer, pH 7.6, ATP formation is determined by monitoring the luminescence using a photomultiplier tube Toxoplasma gondii

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.2.2 ADP + carbamoyl phosphate The parasite actively transports arginine and ornithine, which are converted via the arginine dihydrolase pathway to citrulline and carbamoyl phosphate, resulting in the formation of ATP via carbamate kinase Toxoplasma gondii ATP + NH3 + CO2
-
 ?
2.7.2.2 ADP + carbamoyl phosphate The parasite actively transports arginine and ornithine, which are converted via the arginine dihydrolase pathway to citrulline and carbamoyl phosphate, resulting in the formation of ATP via carbamate kinase Toxoplasma gondii RH ATP + NH3 + CO2
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.2.2 carbamate kinase
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 Toxoplasma gondii