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Literature summary extracted from

  • Wei, M.; Yang, Y.; Niu, M.; Desfosse, L.; Kennedy, R.; Musier-Forsyth, K.; Kleiman, L.
    Inability of HIV-1 produced in murine cells to selectively incorporate primer tRNALys3 (2008), J. Virol., 82, 12049-12059.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
6.1.1.6 expression of His-tagged LysRS in Escherichia coli Homo sapiens
6.1.1.6 expression of His-tagged LysRS in Escherichia coli Mus musculus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
6.1.1.15 Mg2+
-
 Moloney murine leukemia virus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
6.1.1.15 ATP + L-proline + tRNAPro Moloney murine leukemia virus neither GagPol nor prolyl-tRNA synthetase are required for packaging of tRNAPro into MuLV, tRNAPro is used as primer for reverse transcription AMP + diphosphate + L-prolyl-tRNAPro
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
6.1.1.6 Homo sapiens Q15046
-
-
6.1.1.6 Mus musculus Q99MN1
-
-
6.1.1.15 Moloney murine leukemia virus
-
 MuLV, produced in murine cells
-

Purification (Commentary)

EC Number Purification (Comment) Organism
6.1.1.6 Ni+-affinity column Homo sapiens
6.1.1.6 Ni+-affinity column Mus musculus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
6.1.1.6 A-9 cell
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.1.1.15 ATP + L-proline + tRNAPro
-
 Moloney murine leukemia virus AMP + diphosphate + L-prolyl-tRNAPro
-
 ?
6.1.1.15 ATP + L-proline + tRNAPro neither GagPol nor prolyl-tRNA synthetase are required for packaging of tRNAPro into MuLV, tRNAPro is used as primer for reverse transcription Moloney murine leukemia virus AMP + diphosphate + L-prolyl-tRNAPro
-
 ?

Synonyms

EC Number Synonyms Comment Organism
6.1.1.6 LysRS
-
 Homo sapiens
6.1.1.6 LysRS
-
 Mus musculus
6.1.1.6 Lysyl-tRNA synthetase
-
 Homo sapiens
6.1.1.6 Lysyl-tRNA synthetase
-
 Mus musculus

Cofactor

EC Number Cofactor Comment Organism Structure
6.1.1.15 ATP
-
 Moloney murine leukemia virus