BRENDA - Enzyme Database

Molecular modeling and dynamics studies of cytidylate kinase from Mycobacterium tuberculosis H37Rv

Caceres, R.A.; Macedo Timmers, L.F.; Vivan, A.L.; Schneider, C.Z.; Basso, L.A.; De Azevedo, W.F.; Santos, D.S.; J. Mol. Model. 14, 427-434 (2008)

Data extracted from this reference:

Cloned(Commentary)
EC Number
Commentary
Organism
2.7.4.25
expressed in Escherichia coli BL21(DE3) cells
Mycobacterium tuberculosis
Metals/Ions
EC Number
Metals/Ions
Commentary
Organism
Structure
2.7.4.25
Mg2+
-
Mycobacterium tuberculosis
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
2.7.4.25
ATP + CMP
Mycobacterium tuberculosis
-
ADP + CDP
-
-
?
2.7.4.25
ATP + CMP
Mycobacterium tuberculosis H37Rv
-
ADP + CDP
-
-
?
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
2.7.4.25
Mycobacterium tuberculosis
-
strain H37Rv
-
2.7.4.25
Mycobacterium tuberculosis
P9WPA9
-
-
2.7.4.25
Mycobacterium tuberculosis H37Rv
P9WPA9
-
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.7.4.25
ATP + CMP
-
693707
Mycobacterium tuberculosis
ADP + CDP
-
-
-
?
2.7.4.25
ATP + CMP
-
693707
Mycobacterium tuberculosis H37Rv
ADP + CDP
-
-
-
?
2.7.4.25
ATP + dCMP
-
693707
Mycobacterium tuberculosis
ADP + dCDP
-
-
-
?
2.7.4.25
additional information
modelling of CMPK in apo form and in complex with cytidine 5'-monophosphate, structure analysis, overview
693707
Mycobacterium tuberculosis
?
-
-
-
-
2.7.4.25
additional information
modelling of CMPK in apo form and in complex with cytidine 5'-monophosphate, structure analysis, overview
693707
Mycobacterium tuberculosis H37Rv
?
-
-
-
-
Subunits
EC Number
Subunits
Commentary
Organism
2.7.4.25
More
enzyme structure modelling with or without bound substrate, molecular dynamics simulations, comparative analysis, overview
Mycobacterium tuberculosis
Cofactor
EC Number
Cofactor
Commentary
Organism
Structure
2.7.4.25
ATP
;
Mycobacterium tuberculosis
Cloned(Commentary) (protein specific)
EC Number
Commentary
Organism
2.7.4.25
expressed in Escherichia coli BL21(DE3) cells
Mycobacterium tuberculosis
Cofactor (protein specific)
EC Number
Cofactor
Commentary
Organism
Structure
2.7.4.25
ATP
-
Mycobacterium tuberculosis
Metals/Ions (protein specific)
EC Number
Metals/Ions
Commentary
Organism
Structure
2.7.4.25
Mg2+
-
Mycobacterium tuberculosis
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
2.7.4.25
ATP + CMP
Mycobacterium tuberculosis
-
ADP + CDP
-
-
?
2.7.4.25
ATP + CMP
Mycobacterium tuberculosis H37Rv
-
ADP + CDP
-
-
?
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.7.4.25
ATP + CMP
-
693707
Mycobacterium tuberculosis
ADP + CDP
-
-
-
?
2.7.4.25
ATP + CMP
-
693707
Mycobacterium tuberculosis H37Rv
ADP + CDP
-
-
-
?
2.7.4.25
ATP + dCMP
-
693707
Mycobacterium tuberculosis
ADP + dCDP
-
-
-
?
2.7.4.25
additional information
modelling of CMPK in apo form and in complex with cytidine 5'-monophosphate, structure analysis, overview
693707
Mycobacterium tuberculosis
?
-
-
-
-
2.7.4.25
additional information
modelling of CMPK in apo form and in complex with cytidine 5'-monophosphate, structure analysis, overview
693707
Mycobacterium tuberculosis H37Rv
?
-
-
-
-
Subunits (protein specific)
EC Number
Subunits
Commentary
Organism
2.7.4.25
More
enzyme structure modelling with or without bound substrate, molecular dynamics simulations, comparative analysis, overview
Mycobacterium tuberculosis