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Literature summary extracted from

  • Caceres, R.A.; Macedo Timmers, L.F.; Vivan, A.L.; Schneider, C.Z.; Basso, L.A.; De Azevedo, W.F.; Santos, D.S.
    Molecular modeling and dynamics studies of cytidylate kinase from Mycobacterium tuberculosis H37Rv (2008), J. Mol. Model., 14, 427-434.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.4.25 expressed in Escherichia coli BL21(DE3) cells Mycobacterium tuberculosis

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.7.4.25 Mg2+
-
 Mycobacterium tuberculosis

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.4.25 ATP + CMP Mycobacterium tuberculosis
-
 ADP + CDP
-
 ?
2.7.4.25 ATP + CMP Mycobacterium tuberculosis H37Rv
-
 ADP + CDP
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.4.25 Mycobacterium tuberculosis
-
 strain H37Rv
-
2.7.4.25 Mycobacterium tuberculosis P9WPA9
-
-
2.7.4.25 Mycobacterium tuberculosis H37Rv P9WPA9
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.4.25 ATP + CMP
-
 Mycobacterium tuberculosis ADP + CDP
-
 ?
2.7.4.25 ATP + CMP
-
 Mycobacterium tuberculosis H37Rv ADP + CDP
-
 ?
2.7.4.25 ATP + dCMP
-
 Mycobacterium tuberculosis ADP + dCDP
-
 ?
2.7.4.25 additional information modelling of CMPK in apo form and in complex with cytidine 5'-monophosphate, structure analysis, overview Mycobacterium tuberculosis ?
-
 ?
2.7.4.25 additional information modelling of CMPK in apo form and in complex with cytidine 5'-monophosphate, structure analysis, overview Mycobacterium tuberculosis H37Rv ?
-
 ?

Subunits

EC Number Subunits Comment Organism
2.7.4.25 More enzyme structure modelling with or without bound substrate, molecular dynamics simulations, comparative analysis, overview Mycobacterium tuberculosis

Synonyms

EC Number Synonyms Comment Organism
2.7.4.25 bacterial cytidylate kinase
-
 Mycobacterium tuberculosis
2.7.4.25 CMP kinase
-
 Mycobacterium tuberculosis
2.7.4.25 CMPK
-
 Mycobacterium tuberculosis
2.7.4.25 cytidine monophosphate kinase
-
 Mycobacterium tuberculosis
2.7.4.25 cytidylate kinase
-
 Mycobacterium tuberculosis
2.7.4.25 More CMP kinases belong to the nucleoside monophosphate kinase, NMK, family, key enzymes in the metabolism of nucleotides Mycobacterium tuberculosis

Cofactor

EC Number Cofactor Comment Organism Structure
2.7.4.25 ATP
-
 Mycobacterium tuberculosis