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Literature summary extracted from

  • Hodak, H.; Wohlkoenig, A.; Smet-Nocca, C.; Drobecq, H.; Wieruszeski, J.M.; Senechal, M.; Landrieu, I.; Locht, C.; Jamin, M.; Jacob-Dubuisson, F.
    The peptidyl-prolyl isomerase and chaperone Par27 of Bordetella pertussis as the prototype for a new group of parvulins (2008), J. Mol. Biol., 376, 414-426.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
5.2.1.8 additional information
-
 RNase T1 ratio kcat/Km value of 43 per mM and s, pH 6.6 Bordetella pertussis

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
5.2.1.8 periplasm
-
 Bordetella pertussis
-
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
5.2.1.8 27000
-
 2 * 27000, SDS-PAGE, 2 * 27034, calculated Bordetella pertussis
5.2.1.8 27034
-
 2 * 27000, SDS-PAGE, 2 * 27034, calculated Bordetella pertussis

Organism

EC Number Organism UniProt Comment Textmining
5.2.1.8 Bordetella pertussis P40415 Par27 belongs to parvulin family
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
5.2.1.8 proteolytic modification sequence contains a N-terminal signal peptide, with a putative cleavage site between residues A19 and Q20 Bordetella pertussis

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.2.1.8 additional information isoform Par27 displays both prolyl-peptidyl isomerase and chaperone activities in vitro Bordetella pertussis ?
-
 ?
5.2.1.8 RNAse T1
-
 Bordetella pertussis ?
-
 ?
5.2.1.8 VYKS-(cis)-PVVSGDTS-(cis)-PRHL interconversion occurs at both P5 and P13 Bordetella pertussis VYKS-(trans)-PVVSGDTS-(trans)-PRHL
-
 ?

Subunits

EC Number Subunits Comment Organism
5.2.1.8 dimer 2 * 27000, SDS-PAGE, 2 * 27034, calculated Bordetella pertussis
5.2.1.8 More isoform Par27 binds to an unfolded filamentous hemagglutinin fragment Bordetella pertussis

Synonyms

EC Number Synonyms Comment Organism
5.2.1.8 Par27
-
 Bordetella pertussis

pI Value

EC Number Organism Comment pI Value Maximum pI Value
5.2.1.8 Bordetella pertussis calculated
-
 8.1