Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Tie, A.; Bakovic, M.
    Alternative splicing of CTP:phosphoethanolamine cytidylyltransferase produces two isoforms that differ in catalytic properties (2007), J. Lipid Res., 48, 2172-2181.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.7.14 expressed in COS-7 cells Mus musculus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.7.7.14 0.08409
-
 CTP isozyme Pcyt2beta, at 37°C Mus musculus
2.7.7.14 0.102
-
 CTP isozyme Pcyt2alpha, at 37°C Mus musculus
2.7.7.14 0.1403
-
 Ethanolamine phosphate isozyme Pcyt2beta, at 37°C Mus musculus
2.7.7.14 0.3184
-
 Ethanolamine phosphate isozyme Pcyt2alpha, at 37°C Mus musculus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.7.7.14 90000
-
 myc-His-tagged Pcyt2beta, appears as two bands (110000 and 90000 Da), gel filtration Mus musculus
2.7.7.14 108000
-
 myc-His-tagged Pcyt2alpha, gel filtration Mus musculus
2.7.7.14 110000
-
 myc-His-tagged Pcyt2beta, appears as two bands (110000 and 90000 Da), gel filtration Mus musculus

Organism

EC Number Organism UniProt Comment Textmining
2.7.7.14 Mus musculus Q922E4
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.7.7.14 Ni-NTA Superflow resin chromatography Mus musculus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.7.14 adipose tissue
-
 Mus musculus
-
2.7.7.14 brain
-
 Mus musculus
-
2.7.7.14 heart
-
 Mus musculus
-
2.7.7.14 kidney
-
 Mus musculus
-
2.7.7.14 liver
-
 Mus musculus
-
2.7.7.14 skeletal muscle
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.7.14 CTP + ethanolamine phosphate
-
 Mus musculus diphosphate + CDP-ethanolamine
-
 ?

Subunits

EC Number Subunits Comment Organism
2.7.7.14 dimer isozymes Pcyt2alpha and Pcyt2beta proteins can form both homodimeric and heterodimeric complexes Mus musculus

Synonyms

EC Number Synonyms Comment Organism
2.7.7.14 CTP:phosphoethanolamine cytidylyltransferase
-
 Mus musculus
2.7.7.14 Pcyt2
-
 Mus musculus
2.7.7.14 Pcyt2alpha isozyme Mus musculus
2.7.7.14 Pcyt2beta isozyme Mus musculus