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Literature summary extracted from

  • Su, J.; Chai, X.; Kahn, B.; Napoli, J.L.
    cDNA cloning, tissue distribution, and substrate characteristics of a cis-Retinol/3alpha-hydroxysterol short-chain dehydrogenase isozyme. (1998), J. Biol. Chem., 273, 17910-17916.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.1.1.315 expressed in CHO cells Mus musculus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.1.1.315 additional information
-
 additional information cooperative kinetics Mus musculus

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.315 Mus musculus O88451
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.315 liver intense expression of CRAD2 mRNA Mus musculus
-
1.1.1.315 lung expression of CRAD2 mRNA is 3% of that in liver Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.315 11-cis-retinol + NAD+ activity with NAD+ is about 10fold higher than with NADP+ Mus musculus 11-cis-retinal + NADH + H+
-
 ?
1.1.1.315 11-cis-retinol + NADP+ activity with NAD+ is about 10fold higher than with NADP+ Mus musculus 11-cis-retinal + NADPH + H+
-
 ?
1.1.1.315 13-cis-retinol + NAD+
-
 Mus musculus 13-cis-retinal + NADH + H+
-
 ?
1.1.1.315 9-cis-retinol + NAD+ activity with NAD+ is about 8fold higher than with NADP+ Mus musculus 9-cis-retinal + NADH + H+
-
 ?
1.1.1.315 9-cis-retinol + NADP+ activity with NAD+ is about 8fold higher than with NADP+ Mus musculus 9-cis-retinal + NADPH + H+
-
 ?
1.1.1.315 all-trans-retinol + NAD+
-
 Mus musculus all-trans-retinal + NADH + H+
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.1.1.315 cis-retinol/3alpha-hydroxysterol short-chain dehydrogenase multifunctional enzyme Mus musculus
1.1.1.315 CRAD2
-
 Mus musculus

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.315 NAD+ activity with NAD+ is about 10fold higher than with NADP+ Mus musculus
1.1.1.315 NADP+ activity with NAD+ is about 10fold higher than with NADP+ Mus musculus