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Literature summary extracted from

  • Tong, H.; Chen, W.; Shi, W.; Qi, F.; Dong, X.
    SO-LAAO, a novel L-amino acid oxidase that enables Streptococcus oligofermentans to outcompete Streptococcus mutans by generating H2O2 from peptone (2008), J. Bacteriol., 190, 4716-4721.
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.4.3.2 additional information peptone up-regulates expression of the aaoSo gene Streptococcus cristatus

Application

EC Number Application Comment Organism
1.4.3.2 additional information LAAO contributes to competitive edge of Streptococcus oligofermentans over Streptococcus mutans in mixed-species biofilm with peptone Streptococcus cristatus

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.4.3.2 overexpressed in Escherichia coli BL21(DE3)pLysS Streptococcus cristatus

Protein Variants

EC Number Protein Variants Comment Organism
1.4.3.2 additional information an aaoSo mutant loses H2O2 formation from L-amino acids. Inhibition by Streptococcus oligofermentans of Streptococcus mutans in a peptone-rich mixed-species biofilm is greatly reduced Streptococcus cristatus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.4.3.2 43000
-
 x * 43000, SDS-PAGE Streptococcus cristatus

Organism

EC Number Organism UniProt Comment Textmining
1.4.3.2 Streptococcus cristatus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.4.3.2 by immobilized metal ion affinity chromatography Streptococcus cristatus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.4.3.2 L-arginine + H2O + O2
-
 Streptococcus cristatus 2-oxo-5-guanidinovaleric acid + NH3 + H2O2
-
 ?
1.4.3.2 L-asparagine + H2O + O2
-
 Streptococcus cristatus alpha-ketosuccinamic acid + NH3 + H2O2
-
 ?
1.4.3.2 L-aspartic acid + H2O + O2
-
 Streptococcus cristatus oxaloacetate + NH3 + H2O2
-
 ?
1.4.3.2 L-glutamine + H2O + O2
-
 Streptococcus cristatus 5-amino-2,5-dioxopentanoate + NH3 + H2O2
-
 ?
1.4.3.2 L-isoleucine + H2O + O2
-
 Streptococcus cristatus alpha-keto-beta-methyl-pentanoic acid + NH3 + H2O2
-
 ?
1.4.3.2 L-lysine + H2O + O2
-
 Streptococcus cristatus 6-amino-2-oxohexanoic acid + NH3 + H2O2
-
 ?
1.4.3.2 L-tryptophan + H2O + O2
-
 Streptococcus cristatus 3-indole-2-oxopropanoate + NH3 + H2O2
-
 ?
1.4.3.2 additional information does not catalyze N-acetyL-L-cysteine and cis-4-hydroxyl-L-proline oxidation Streptococcus cristatus ?
-
 ?

Subunits

EC Number Subunits Comment Organism
1.4.3.2 ? x * 43000, SDS-PAGE Streptococcus cristatus

Synonyms

EC Number Synonyms Comment Organism
1.4.3.2 LAAO
-
 Streptococcus cristatus