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Literature summary extracted from
- Reduction of Hg2+ with reduced mammalian cytochrome c by cytochrome c oxidase purified from a mercury-resistant acidithiobacillus ferrooxidans strain, MON-1 (2008), Biosci. Biotechnol. Biochem., 72, 1756-1763.
Application
| EC Number | Application | Comment | Organism |
|---|---|---|---|
| 7.1.1.9 | additional information | cytochrome c oxidase is involved in mercury reduction in Acidithiobacillus ferrooxidans cells. Levels of mercury resistance in Acidithiobacillus ferrooxidans strains correspond well with the levels of mercury resistance of cytochrome c oxidase | Acidithiobacillus ferrooxidans |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 7.1.1.9 | Hg2+ | cytochrome c oxidase activities of strains AP19-3 and ATCC 23270 are completely inhibited by 0.001 mM and 0.005 mM. Strain MON-1 is inhibited 33% by 0.005 mM, and 70% by 0.010 mM | Acidithiobacillus ferrooxidans |  |
| 7.1.1.9 | NaCN | 1 mM completely inhibits mercury volatilization activities with reduced cytochrome c and 2,3,5,6-tetramethyl-p-phenylendiamine in strain MON-1 | Acidithiobacillus ferrooxidans | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 7.1.1.9 | Acidithiobacillus ferrooxidans | - |
strains MON-1, AP19-3 and ATCC 23270 | - |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 7.1.1.9 | strain MON-1 purified 19.4fold by gel filtration | Acidithiobacillus ferrooxidans |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 7.1.1.9 | 2.7 | - |
strain MON-1 | Acidithiobacillus ferrooxidans |
| 7.1.1.9 | 52.5 | - |
strain MON-1, 19.4fold purified | Acidithiobacillus ferrooxidans |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 7.1.1.9 | 2,3,5,6-tetramethyl-p-phenylendiamine + O2 + H+ | - |
Acidithiobacillus ferrooxidans | ? + H2O | - |
? | |
| 7.1.1.9 | reduced horse cytochrome c + O2 + H+ | - |
Acidithiobacillus ferrooxidans | oxidized horse cytochrome c + H2O | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 7.1.1.9 | cytochrome c oxidase | - |
Acidithiobacillus ferrooxidans |
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