EC Number | Cloned (Comment) | Organism |
---|---|---|
2.7.7.19 | PAPgamma(1-683C), a C-terminally truncated version of full length human PAPgamma with the same catalytic efficiency is expressed in Escherichia coli | Homo sapiens |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.7.7.19 | 5-epi-sisomycin | pH-dependent inhibition, non-competitive inhibitor for ATP | Homo sapiens | |
2.7.7.19 | hygromycin B | pH-dependent inhibition | Homo sapiens | |
2.7.7.19 | kanamycin A | pH-dependent inhibition | Homo sapiens | |
2.7.7.19 | kanamycin B | pH-dependent inhibition | Homo sapiens | |
2.7.7.19 | lividomycin A | pH-dependent inhibition | Homo sapiens | |
2.7.7.19 | additional information | not inhibited by neamine | Homo sapiens | |
2.7.7.19 | neomycin B | an increase in pH releases the neomycin B inhibitory effect on PAPgamma | Homo sapiens | |
2.7.7.19 | paromomycin | pH-dependent inhibition | Homo sapiens | |
2.7.7.19 | ribostamycin | pH-dependent inhibition | Homo sapiens | |
2.7.7.19 | sisomicin | pH-dependent inhibition, non-competitive inhibitor for ATP | Homo sapiens | |
2.7.7.19 | tobramycin | pH-dependent inhibition | Homo sapiens |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
2.7.7.19 | Mg2+ | Mg2+ ions can release the inhibition of PAPgamma by aminoglycosides | Homo sapiens |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.7.19 | additional information | Homo sapiens | the enzyme is responsible for the synthesis of the poly(A) tail at the 3'-end of eukaryotic mRNA | ? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.7.7.19 | Homo sapiens | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
2.7.7.19 | - |
Homo sapiens |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.7.19 | ATP + RNA | - |
Homo sapiens | diphosphate + RNA(A)n | - |
? | |
2.7.7.19 | additional information | the enzyme is responsible for the synthesis of the poly(A) tail at the 3'-end of eukaryotic mRNA | Homo sapiens | ? | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.7.7.19 | PAPgamma | - |
Homo sapiens |
2.7.7.19 | poly(A) polymerase gamma | - |
Homo sapiens |