Literature summary extracted from

Kondo, Y.; Sasaki, T.; Sato, Y.; Amano, A.; Aizawa, S.; Iwama, M.; Handa, S.; Shimada, N.; Fukuda, M.; Akita, M.; Lee, J.; Jeong, K.S.; Maruyama, N.; Ishigami, A.
Vitamin C depletion increases superoxide generation in brains of SMP30/GNL knockout mice (2008), Biochem. Biophys. Res. Commun., 377, 291-296.

Protein Variants

EC Number	Protein Variants	Comment	Organism
3.1.1.17	additional information	SMP30/GNL knockout mice lack the ability to synthesize vitamin C in vivo	Mus musculus

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
3.1.1.17	additional information	Mus musculus	GNL is a key enzyme involved in vitamin C biosynthesis	?	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.1.1.17	Mus musculus	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
3.1.1.17	D-glucono-1,5-lactone + H2O	-	Mus musculus	D-gluconate	-	?
3.1.1.17	additional information	GNL is a key enzyme involved in vitamin C biosynthesis	Mus musculus	?	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
3.1.1.17	GNL	-	Mus musculus
3.1.1.17	SMP30	-	Mus musculus
3.1.1.17	SMP30/GNL	-	Mus musculus

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Release 2023.1 (January 2023)