EC Number | General Stability | Organism |
---|---|---|
4.2.1.110 | Microthecin is found to be most stable in de-ionized water at a pH around 7.0 and stable in freeze-dried form. Under acidic conditions microthecin is degraded to 2-furyl-2-hydroxymethylketone (FHMK). | Phanerodontia chrysosporium |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
4.2.1.110 | 1,5-Anhydro-D-fructose | substrate inhibition to AUDH at a concentration up to 10% (w/v) | Phanerodontia chrysosporium | |
4.2.1.110 | microthecin | product inhibition to AUDH at a concentration up to 10% (w/v) | Phanerodontia chrysosporium |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
4.2.1.110 | 4.9 | - |
glucosone | - |
Phanerodontia chrysosporium | |
4.2.1.110 | 5.4 | - |
1,5-Anhydro-D-fructose | - |
Phanerodontia chrysosporium |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.2.1.110 | glucosone | Phanerodontia chrysosporium | 2-keto glucose | cortalcerone + H2O | - |
? |
EC Number | Organic Solvent | Comment | Organism |
---|---|---|---|
4.2.1.110 | additional information | the best solvent for AUDH-catalysed microthecin reaction is de-ionized water | Phanerodontia chrysosporium |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
4.2.1.110 | Phanerodontia chrysosporium | P84193 | - |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.2.1.110 | 1,5-anhydro-D-fructose | - |
Phanerodontia chrysosporium | 2-hydroxy-2-(hydroxymethyl)-2H-pyran-3(6H)-one + H2O | microthecin + H2O | ? | |
4.2.1.110 | glucosone | 2-keto glucose | Phanerodontia chrysosporium | cortalcerone + H2O | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
4.2.1.110 | aldos-2-ulose dehydratase | bifunctional enzyme | Phanerodontia chrysosporium |
4.2.1.110 | AUDH | - |
Phanerodontia chrysosporium |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
4.2.1.110 | 24 | - |
at temperatures higher than 24°C there is increased degradation of microthecin | Phanerodontia chrysosporium |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
4.2.1.110 | additional information | - |
the reaction medium acidifies by itself due to unknown events related to the AUDH catalysed reaction | Phanerodontia chrysosporium |
4.2.1.110 | 5 | - |
at a pH lower than 5.0, the reaction rate is slower and there is a tendency for increased formation of degradation products (FHMK), at a pH higher than 5.5, there is a tendency for more APT dihydrate formation | Phanerodontia chrysosporium |
EC Number | pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|---|
4.2.1.110 | additional information | - |
at a pH lower than 5.0, the reaction rate is slower and there is a tendency for increased formation of degradation products (FHMK), at a pH higher than 5.5, there is a tendency for more APT dihydrate formation | Phanerodontia chrysosporium |