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Literature summary extracted from

  • Qiu, G.; Hill, J.S.
    Endothelial lipase promotes apolipoprotein AI-mediated cholesterol efflux in THP-1 macrophages (2009), Arterioscler. Thromb. Vasc. Biol., 29, 84-91.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.1.1.32 expressed in HEK-293 cells Homo sapiens

Protein Variants

EC Number Protein Variants Comment Organism
3.1.1.32 S149A catalytically inactive Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.1.32 tetrahydrolipstatin
-
 Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.32 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.1.32 macrophage
-
 Homo sapiens
-
3.1.1.32 THP-1 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.32 phosphatidylcholine + H2O
-
 Homo sapiens 2-acylglycerophosphocholine + a fatty acid anion
-
 ?
3.1.1.32 phosphatidylethanolamine + H2O
-
 Homo sapiens lysophosphatidylethanolamine + a fatty acid anion
-
 ?
3.1.1.32 sphingomyelin + H2O
-
 Homo sapiens ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.1.1.32 endothelial lipase
-
 Homo sapiens