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Literature summary extracted from

  • Loetzer, K.; Jahn, S.; Kramer, C.; Hildner, M.; Nuesing, R.; Funk, C.D.; Habenicht, A.J.
    5-Lipoxygenase/cyclooxygenase-2 cross-talk through cysteinyl leukotriene receptor 2 in endothelial cells (2007), Prostaglandins Other Lipid Mediat., 84, 108-115.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.13.11.34 (6E,8Z,11Z,14Z)-(5S)-5-hydroperoxyeicosa-6,8,11,14-tetraenoate Homo sapiens
-
 leukotriene A4 + H2O is unstable and metabolized to leukotriene B4 ?
1.13.11.34 arachidonic acid + O2 Homo sapiens
-
 (6E,8Z,11Z,14Z)-(5S)-5-hydroperoxyeicosa-6,8,11,14-tetraenoate
-
 ?
1.13.11.34 additional information Homo sapiens 5-lipoxygenase/cyclooxygenase-2 cross-talk through cysteinyl leukotriene receptor 2 in endothelial cells, overview ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.13.11.34 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.13.11.34 umbilical vein endothelial cell 5-lipoxygenase/cyclooxygenase-2 cross-talk through cysteinyl leukotriene receptor 2 in endothelial cells, overview Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.13.11.34 (6E,8Z,11Z,14Z)-(5S)-5-hydroperoxyeicosa-6,8,11,14-tetraenoate
-
 Homo sapiens leukotriene A4 + H2O
-
 ?
1.13.11.34 (6E,8Z,11Z,14Z)-(5S)-5-hydroperoxyeicosa-6,8,11,14-tetraenoate
-
 Homo sapiens leukotriene A4 + H2O is unstable and metabolized to leukotriene B4 ?
1.13.11.34 arachidonic acid + O2
-
 Homo sapiens (6E,8Z,11Z,14Z)-(5S)-5-hydroperoxyeicosa-6,8,11,14-tetraenoate
-
 ?
1.13.11.34 additional information 5-lipoxygenase/cyclooxygenase-2 cross-talk through cysteinyl leukotriene receptor 2 in endothelial cells, overview Homo sapiens ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.13.11.34 5-lipoxygenase
-
 Homo sapiens
1.13.11.34 5-LO
-
 Homo sapiens