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Literature summary extracted from

  • Alfieri, A.; Fersini, F.; Ruangchan, N.; Prongjit, M.; Chaiyen, P.; Mattevi, A.
    Structure of the monooxygenase component of a two-component flavoprotein monooxygenase (2007), Proc. Natl. Acad. Sci. USA, 104, 1177-1182.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.14.9 4-hydroxyphenylacetate + NADH + H+ + O2 Acinetobacter baumannii
-
 3,4-dihydroxyphenylacetate + NAD+ + H2O
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.14.14.9 Acinetobacter baumannii Q6Q272
-
-

Reaction

EC Number Reaction Comment Organism Reaction ID
1.14.14.9 4-hydroxyphenylacetate + FADH2 + O2 = 3,4-dihydroxyphenylacetate + FAD + H2O catalytic mechanism and structure-function relationship, overview Acinetobacter baumannii
a

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.14.9 4-hydroxyphenylacetate + NADH + H+ + O2
-
 Acinetobacter baumannii 3,4-dihydroxyphenylacetate + NAD+ + H2O
-
 ?
1.14.14.9 4-hydroxyphenylacetate + NADH + H+ + O2 substrate binding, catalytic mechanism and structure-function relationship, overview Acinetobacter baumannii 3,4-dihydroxyphenylacetate + NAD+ + H2O
-
 ?
1.14.14.9 additional information the enzyme is a two-component system consisting of a NADH-dependent FMN reductase and a monooxygenase C2, that uses reduced FMN as substrate, structure-function relationship, overview Acinetobacter baumannii ?
-
 ?

Subunits

EC Number Subunits Comment Organism
1.14.14.9 More the enzyme is a two-component system consisting of a NADH-dependent FMN reductase and a monooxygenase C2, that uses reduced FMN as substrate, structure analysis, overview Acinetobacter baumannii

Synonyms

EC Number Synonyms Comment Organism
1.14.14.9 p-hydroxyphenylacetate hydroxylase
-
 Acinetobacter baumannii

Cofactor

EC Number Cofactor Comment Organism Structure
1.14.14.9 FMN involved in reaction step 1 catalyzed by the NADH-dependent FMN reductase enzyme component C1 Acinetobacter baumannii
1.14.14.9 FMNH2 involved in reaction step 2 catalyzed by the monooxygenase enzyme component C2 Acinetobacter baumannii
1.14.14.9 NADH
-
 Acinetobacter baumannii