EC Number | Cloned (Comment) | Organism |
---|---|---|
1.1.1.261 | phylogenetic analysis | Methanosarcina barkeri |
1.1.1.261 | phylogenetic analysis | Pyrococcus sp. |
1.1.1.261 | phylogenetic analysis | Methanothermobacter thermautotrophicus |
1.1.1.261 | phylogenetic analysis | Pyrococcus furiosus |
1.1.1.261 | phylogenetic analysis | Halobacterium salinarum |
1.1.1.261 | phylogenetic analysis | Thermoplasma acidophilum |
1.1.1.261 | phylogenetic analysis | Aeropyrum pernix |
1.1.1.261 | phylogenetic analysis | Sulfurisphaera tokodaii |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.1.1.261 | additional information | - |
additional information | kinetic analysis | Aeropyrum pernix |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
1.1.1.261 | Zn2+ | required | Methanosarcina barkeri | |
1.1.1.261 | Zn2+ | required | Pyrococcus sp. | |
1.1.1.261 | Zn2+ | required | Methanothermobacter thermautotrophicus | |
1.1.1.261 | Zn2+ | required | Pyrococcus furiosus | |
1.1.1.261 | Zn2+ | required | Halobacterium salinarum | |
1.1.1.261 | Zn2+ | required | Thermoplasma acidophilum | |
1.1.1.261 | Zn2+ | required | Aeropyrum pernix | |
1.1.1.261 | Zn2+ | required | Sulfurisphaera tokodaii |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.1.1.261 | dihydroxyacetonephosphate + NAD(P)H | Sulfurisphaera tokodaii | metabolic pathway possibilities, overview | glycerol 1-phosphate + NAD(P)+ | - |
r | |
1.1.1.261 | dihydroxyacetonephosphate + NAD(P)H | Methanosarcina barkeri | the enzyme is involved in formation of the enantiomeric glycerophosphate backbone structure of archaeal phospholipids, metabolic pathway possibilities, overview | glycerol 1-phosphate + NAD(P)+ | - |
r | |
1.1.1.261 | dihydroxyacetonephosphate + NAD(P)H | Pyrococcus sp. | the enzyme is involved in formation of the enantiomeric glycerophosphate backbone structure of archaeal phospholipids, metabolic pathway possibilities, overview | glycerol 1-phosphate + NAD(P)+ | - |
r | |
1.1.1.261 | dihydroxyacetonephosphate + NAD(P)H | Pyrococcus furiosus | the enzyme is involved in formation of the enantiomeric glycerophosphate backbone structure of archaeal phospholipids, metabolic pathway possibilities, overview | glycerol 1-phosphate + NAD(P)+ | - |
r | |
1.1.1.261 | dihydroxyacetonephosphate + NAD(P)H | Halobacterium salinarum | the enzyme is involved in formation of the enantiomeric glycerophosphate backbone structure of archaeal phospholipids, metabolic pathway possibilities, overview | glycerol 1-phosphate + NAD(P)+ | - |
r | |
1.1.1.261 | dihydroxyacetonephosphate + NAD(P)H | Thermoplasma acidophilum | the enzyme is involved in formation of the enantiomeric glycerophosphate backbone structure of archaeal phospholipids, metabolic pathway possibilities, overview | glycerol 1-phosphate + NAD(P)+ | - |
r | |
1.1.1.261 | dihydroxyacetonephosphate + NAD(P)H | Aeropyrum pernix | the enzyme is involved in formation of the enantiomeric glycerophosphate backbone structure of archaeal phospholipids, metabolic pathway possibilities, overview | glycerol 1-phosphate + NAD(P)+ | - |
r | |
1.1.1.261 | dihydroxyacetonephosphate + NAD(P)H | Methanothermobacter thermautotrophicus | the enzyme is involved in formation of the enantiomeric glycerophosphate backbone structure of archaeal phospholipids, metabolic pathway possibilities, overview | glycerol-1-phosphate + NAD(P)+ | - |
r | |
1.1.1.261 | dihydroxyacetonephosphate + NAD(P)H | Pyrococcus sp. KS8-1 | the enzyme is involved in formation of the enantiomeric glycerophosphate backbone structure of archaeal phospholipids, metabolic pathway possibilities, overview | glycerol 1-phosphate + NAD(P)+ | - |
r | |
1.1.1.261 | dihydroxyacetonephosphate + NAD(P)H | Thermoplasma acidophilum HO-62 | the enzyme is involved in formation of the enantiomeric glycerophosphate backbone structure of archaeal phospholipids, metabolic pathway possibilities, overview | glycerol 1-phosphate + NAD(P)+ | - |
r |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.1.1.261 | Aeropyrum pernix | - |
- |
- |
1.1.1.261 | Halobacterium salinarum | - |
- |
- |
1.1.1.261 | Methanosarcina barkeri | - |
- |
- |
1.1.1.261 | Methanothermobacter thermautotrophicus | - |
- |
- |
1.1.1.261 | Pyrococcus furiosus | - |
- |
- |
1.1.1.261 | Pyrococcus sp. | - |
- |
- |
1.1.1.261 | Pyrococcus sp. KS8-1 | - |
- |
- |
1.1.1.261 | Sulfurisphaera tokodaii | - |
- |
- |
1.1.1.261 | Thermoplasma acidophilum | - |
- |
- |
1.1.1.261 | Thermoplasma acidophilum HO-62 | - |
- |
- |
EC Number | Reaction | Comment | Organism | Reaction ID |
---|---|---|---|---|
1.1.1.261 | sn-glycerol 1-phosphate + NAD(P)+ = glycerone phosphate + NAD(P)H + H+ | reaction mechanism with transfer of pro-R hydrogen of NAD(P)H and a chiral product | Methanosarcina barkeri | |
1.1.1.261 | sn-glycerol 1-phosphate + NAD(P)+ = glycerone phosphate + NAD(P)H + H+ | reaction mechanism with transfer of pro-R hydrogen of NAD(P)H and a chiral product | Pyrococcus sp. | |
1.1.1.261 | sn-glycerol 1-phosphate + NAD(P)+ = glycerone phosphate + NAD(P)H + H+ | reaction mechanism with transfer of pro-R hydrogen of NAD(P)H and a chiral product | Methanothermobacter thermautotrophicus | |
1.1.1.261 | sn-glycerol 1-phosphate + NAD(P)+ = glycerone phosphate + NAD(P)H + H+ | reaction mechanism with transfer of pro-R hydrogen of NAD(P)H and a chiral product | Pyrococcus furiosus | |
1.1.1.261 | sn-glycerol 1-phosphate + NAD(P)+ = glycerone phosphate + NAD(P)H + H+ | reaction mechanism with transfer of pro-R hydrogen of NAD(P)H and a chiral product | Halobacterium salinarum | |
1.1.1.261 | sn-glycerol 1-phosphate + NAD(P)+ = glycerone phosphate + NAD(P)H + H+ | reaction mechanism with transfer of pro-R hydrogen of NAD(P)H and a chiral product | Thermoplasma acidophilum | |
1.1.1.261 | sn-glycerol 1-phosphate + NAD(P)+ = glycerone phosphate + NAD(P)H + H+ | reaction mechanism with transfer of pro-R hydrogen of NAD(P)H and a chiral product | Aeropyrum pernix | |
1.1.1.261 | sn-glycerol 1-phosphate + NAD(P)+ = glycerone phosphate + NAD(P)H + H+ | reaction mechanism with transfer of pro-R hydrogen of NAD(P)H and a chiral product | Sulfurisphaera tokodaii |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.1.1.261 | dihydroxyacetonephosphate + NAD(P)H | metabolic pathway possibilities, overview | Sulfurisphaera tokodaii | glycerol 1-phosphate + NAD(P)+ | - |
r | |
1.1.1.261 | dihydroxyacetonephosphate + NAD(P)H | the enzyme is involved in formation of the enantiomeric glycerophosphate backbone structure of archaeal phospholipids, metabolic pathway possibilities, overview | Methanosarcina barkeri | glycerol 1-phosphate + NAD(P)+ | - |
r | |
1.1.1.261 | dihydroxyacetonephosphate + NAD(P)H | the enzyme is involved in formation of the enantiomeric glycerophosphate backbone structure of archaeal phospholipids, metabolic pathway possibilities, overview | Pyrococcus sp. | glycerol 1-phosphate + NAD(P)+ | - |
r | |
1.1.1.261 | dihydroxyacetonephosphate + NAD(P)H | the enzyme is involved in formation of the enantiomeric glycerophosphate backbone structure of archaeal phospholipids, metabolic pathway possibilities, overview | Pyrococcus furiosus | glycerol 1-phosphate + NAD(P)+ | - |
r | |
1.1.1.261 | dihydroxyacetonephosphate + NAD(P)H | the enzyme is involved in formation of the enantiomeric glycerophosphate backbone structure of archaeal phospholipids, metabolic pathway possibilities, overview | Halobacterium salinarum | glycerol 1-phosphate + NAD(P)+ | - |
r | |
1.1.1.261 | dihydroxyacetonephosphate + NAD(P)H | the enzyme is involved in formation of the enantiomeric glycerophosphate backbone structure of archaeal phospholipids, metabolic pathway possibilities, overview | Thermoplasma acidophilum | glycerol 1-phosphate + NAD(P)+ | - |
r | |
1.1.1.261 | dihydroxyacetonephosphate + NAD(P)H | the enzyme is involved in formation of the enantiomeric glycerophosphate backbone structure of archaeal phospholipids, metabolic pathway possibilities, overview | Aeropyrum pernix | glycerol 1-phosphate + NAD(P)+ | - |
r | |
1.1.1.261 | dihydroxyacetonephosphate + NAD(P)H | active site structure and molecular mechanism, overview | Methanosarcina barkeri | glycerol 1-phosphate + NAD(P)+ | - |
r | |
1.1.1.261 | dihydroxyacetonephosphate + NAD(P)H | active site structure and molecular mechanism, overview | Pyrococcus sp. | glycerol 1-phosphate + NAD(P)+ | - |
r | |
1.1.1.261 | dihydroxyacetonephosphate + NAD(P)H | active site structure and molecular mechanism, overview | Pyrococcus furiosus | glycerol 1-phosphate + NAD(P)+ | - |
r | |
1.1.1.261 | dihydroxyacetonephosphate + NAD(P)H | active site structure and molecular mechanism, overview | Halobacterium salinarum | glycerol 1-phosphate + NAD(P)+ | - |
r | |
1.1.1.261 | dihydroxyacetonephosphate + NAD(P)H | active site structure and molecular mechanism, overview | Thermoplasma acidophilum | glycerol 1-phosphate + NAD(P)+ | - |
r | |
1.1.1.261 | dihydroxyacetonephosphate + NAD(P)H | active site structure and molecular mechanism, overview | Sulfurisphaera tokodaii | glycerol 1-phosphate + NAD(P)+ | - |
r | |
1.1.1.261 | dihydroxyacetonephosphate + NAD(P)H | active site structure and molecular mechanism, the reduction reaction is preferred, overview | Aeropyrum pernix | glycerol 1-phosphate + NAD(P)+ | - |
r | |
1.1.1.261 | dihydroxyacetonephosphate + NAD(P)H | the enzyme is involved in formation of the enantiomeric glycerophosphate backbone structure of archaeal phospholipids, metabolic pathway possibilities, overview | Pyrococcus sp. KS8-1 | glycerol 1-phosphate + NAD(P)+ | - |
r | |
1.1.1.261 | dihydroxyacetonephosphate + NAD(P)H | active site structure and molecular mechanism, overview | Pyrococcus sp. KS8-1 | glycerol 1-phosphate + NAD(P)+ | - |
r | |
1.1.1.261 | dihydroxyacetonephosphate + NAD(P)H | the enzyme is involved in formation of the enantiomeric glycerophosphate backbone structure of archaeal phospholipids, metabolic pathway possibilities, overview | Thermoplasma acidophilum HO-62 | glycerol 1-phosphate + NAD(P)+ | - |
r | |
1.1.1.261 | dihydroxyacetonephosphate + NAD(P)H | active site structure and molecular mechanism, overview | Thermoplasma acidophilum HO-62 | glycerol 1-phosphate + NAD(P)+ | - |
r | |
1.1.1.261 | dihydroxyacetonephosphate + NAD(P)H | the enzyme is involved in formation of the enantiomeric glycerophosphate backbone structure of archaeal phospholipids, metabolic pathway possibilities, overview | Methanothermobacter thermautotrophicus | glycerol-1-phosphate + NAD(P)+ | - |
r | |
1.1.1.261 | dihydroxyacetonephosphate + NAD(P)H | active site structure and molecular mechanism, overview | Methanothermobacter thermautotrophicus | glycerol-1-phosphate + NAD(P)+ | - |
r |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.1.1.261 | G-1-P dehydrogenase | - |
Methanosarcina barkeri |
1.1.1.261 | G-1-P dehydrogenase | - |
Pyrococcus sp. |
1.1.1.261 | G-1-P dehydrogenase | - |
Methanothermobacter thermautotrophicus |
1.1.1.261 | G-1-P dehydrogenase | - |
Pyrococcus furiosus |
1.1.1.261 | G-1-P dehydrogenase | - |
Halobacterium salinarum |
1.1.1.261 | G-1-P dehydrogenase | - |
Thermoplasma acidophilum |
1.1.1.261 | G-1-P dehydrogenase | - |
Aeropyrum pernix |
1.1.1.261 | G-1-P dehydrogenase | - |
Sulfurisphaera tokodaii |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.1.1.261 | NADH | preferred cofactor | Methanosarcina barkeri | |
1.1.1.261 | NADH | preferred cofactor | Pyrococcus sp. | |
1.1.1.261 | NADH | preferred cofactor | Methanothermobacter thermautotrophicus | |
1.1.1.261 | NADH | preferred cofactor | Pyrococcus furiosus | |
1.1.1.261 | NADH | preferred cofactor | Halobacterium salinarum | |
1.1.1.261 | NADH | preferred cofactor | Thermoplasma acidophilum | |
1.1.1.261 | NADH | preferred cofactor | Aeropyrum pernix | |
1.1.1.261 | NADH | preferred cofactor | Sulfurisphaera tokodaii | |
1.1.1.261 | NADPH | less active than NADH | Methanosarcina barkeri | |
1.1.1.261 | NADPH | less active than NADH | Pyrococcus sp. | |
1.1.1.261 | NADPH | less active than NADH | Methanothermobacter thermautotrophicus | |
1.1.1.261 | NADPH | less active than NADH | Pyrococcus furiosus | |
1.1.1.261 | NADPH | less active than NADH | Halobacterium salinarum | |
1.1.1.261 | NADPH | less active than NADH | Thermoplasma acidophilum | |
1.1.1.261 | NADPH | less active than NADH | Aeropyrum pernix | |
1.1.1.261 | NADPH | less active than NADH | Sulfurisphaera tokodaii |