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Literature summary extracted from

  • Lengi, A.J.; Corl, B.A.
    Identification and characterization of a novel bovine stearoyl-CoA desaturase isoform with homology to human SCD5 (2007), Lipids, 42, 499-508.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.14.19.1 gene SCD1, phylogenetic tree, sequence comparisons with other isozymes and enzymes from other organisms, overview Bos taurus
1.14.19.1 gene SCD5, DNA and amino acid sequence determination and analysis, phylogenetic tree, sequence comparisons with other isozymes and enzymes from other organisms, overview Bos taurus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.19.1 stearoyl-CoA + ferrocytochrome b5 + O2 + H+ Bos taurus
-
oleoyl-CoA + ferricytochrome b5 + H2O
-
?

Organism

EC Number Organism UniProt Comment Textmining
1.14.19.1 Bos taurus Q2KIA4 isozyme SCD5; isozyme SCD5
-
1.14.19.1 Bos taurus Q9TT94 isozyme SCD1; isozyme SCD1
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.14.19.1 adipose tissue high expression level of isozyme SCD1 Bos taurus
-
1.14.19.1 adipose tissue low expression level of isozyme SCD1 Bos taurus
-
1.14.19.1 brain
-
Bos taurus
-
1.14.19.1 brain specific high expression level of isozyme SCD5, equally distributed between white and gray matter Bos taurus
-
1.14.19.1 heart
-
Bos taurus
-
1.14.19.1 heart low expression level of isozyme SCD1 Bos taurus
-
1.14.19.1 liver low expression level of isozyme SCD1 Bos taurus
-
1.14.19.1 lung
-
Bos taurus
-
1.14.19.1 additional information no expression of isozyme SCD5 in lung Bos taurus
-
1.14.19.1 skeletal muscle
-
Bos taurus
-
1.14.19.1 skeletal muscle low expression level of isozyme SCD1 Bos taurus
-
1.14.19.1 spleen low expression level of isozyme SCD1 Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.19.1 additional information the enzyme also produces cis-9, trans-11 conjugated linoleic acid and palmitoleoyl-CoA Bos taurus ?
-
?
1.14.19.1 stearoyl-CoA + ferrocytochrome b5 + O2 + H+
-
Bos taurus oleoyl-CoA + ferricytochrome b5 + H2O
-
?

Synonyms

EC Number Synonyms Comment Organism
1.14.19.1 SCD
-
Bos taurus
1.14.19.1 SCD1
-
Bos taurus
1.14.19.1 stearoyl-CoA desaturase
-
Bos taurus

Cofactor

EC Number Cofactor Comment Organism Structure
1.14.19.1 ferrocytochrome b5
-
Bos taurus