EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.1.1.34 | GFPTGG | competitive, effects on enzyme Michaelis-Menten kinetics, overview | Rattus norvegicus | |
1.1.1.34 | GLPTGG | competitive | Rattus norvegicus | |
1.1.1.34 | additional information | design, synthesis and evaluation of structure-based peptide inhibitors, computational methods, overview | Rattus norvegicus |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.1.1.34 | 0.068 | - |
hydroxymethylglutaryl-CoA | - |
Rattus norvegicus |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
1.1.1.34 | microsome | - |
Rattus norvegicus | - |
- |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.1.1.34 | hydroxymethylglutaryl-CoA + NADPH + H+ | Rattus norvegicus | - |
mevalonate + NADP+ + CoA | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.1.1.34 | Rattus norvegicus | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.1.1.34 | liver | - |
Rattus norvegicus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.1.1.34 | hydroxymethylglutaryl-CoA + NADPH + H+ | - |
Rattus norvegicus | mevalonate + NADP+ + CoA | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.1.1.34 | HMG-CoA reductase | - |
Rattus norvegicus |
1.1.1.34 | HMGR | - |
Rattus norvegicus |
EC Number | Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.1.1.34 | 0.023 | - |
hydroxymethylglutaryl-CoA | - |
Rattus norvegicus |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.1.1.34 | NADPH | - |
Rattus norvegicus |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.1.1.34 | 0.0064 | - |
GFPTGG | - |
Rattus norvegicus |