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Literature summary extracted from

  • Blanchard, P.G.; Luu-The, V.
    Differential androgen and estrogen substrates specificity in the mouse and primates type 12 17beta-hydroxysteroid dehydrogenase (2007), J. Endocrinol., 194, 449-455.
    View publication on PubMed

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.62 Mus musculus Q0VGQ1 HEK-293 cells stably expressing 17beta-HSD12
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Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.62 adipose tissue retroperitonea, high mRNA expression Mus musculus
-
1.1.1.62 adrenal gland low mRNA expression Mus musculus
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1.1.1.62 bronchus low mRNA expression Mus musculus
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1.1.1.62 clitoral gland high mRNA expression Mus musculus
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1.1.1.62 colon low mRNA expression Mus musculus
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1.1.1.62 heart low mRNA expression Mus musculus
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1.1.1.62 kidney low mRNA expression Mus musculus
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1.1.1.62 liver low mRNA expression Mus musculus
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1.1.1.62 mammary gland low mRNA expression Mus musculus
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1.1.1.62 ovary low mRNA expression Mus musculus
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1.1.1.62 pituitary gland low mRNA expression Mus musculus
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1.1.1.62 preputial gland high mRNA expression Mus musculus
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1.1.1.62 spleen low mRNA expression Mus musculus
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1.1.1.62 stomach low mRNA expression Mus musculus
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1.1.1.62 thymus low mRNA expression Mus musculus
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1.1.1.62 uterus low mRNA expression Mus musculus
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1.1.1.62 vagina low mRNA expression Mus musculus
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.62 4-androstenedione + NAD(P)H + H+
-
 Mus musculus testosterone + NAD(P)+
-
 ?
1.1.1.62 androsterone + NAD(P)H
-
 Mus musculus 5alpha-androstane-3alpha,17beta-diol + NAD(P)+ + H+
-
 ?
1.1.1.62 dehydroepiandrosterone + NAD(P)H
-
 Mus musculus 5-androstene-3beta,17beta-diol + NAD(P)+
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.1.1.62 17beta-HSD12
-
 Mus musculus