Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Sacchi, S.; Bernasconi, M.; Martineau, M.; Mothet, J.P.; Ruzzene, M.; Pilone, M.S.; Pollegioni, L.; Molla, G.
    pLG72 modulates intracellular D-serine levels through its interaction with D-amino acid oxidase: Effect on schizophrenia susceptibility (2008), J. Biol. Chem., 283, 22244-22256.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.4.3.3 expressed in glioblastoma cells Homo sapiens
1.4.3.3 expressed in glioblastoma cells Sus scrofa

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.4.3.3 additional information bovine serum albumin does not affect DAAO activity Sus scrofa
1.4.3.3 pLG72 acts as a negative effector of DAAO Homo sapiens
1.4.3.3 pLG72 activity decreases in the presence of pLG72 (0.27 mg/ml) Sus scrofa

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.4.3.3 40000
-
 2 * 40000, SDS-PAGE Homo sapiens
1.4.3.3 40000
-
 2 * 40000, SDS-PAGE Sus scrofa
1.4.3.3 80000
-
 SDS-PAGE Homo sapiens
1.4.3.3 80000
-
 SDS-PAGE Sus scrofa

Organism

EC Number Organism UniProt Comment Textmining
1.4.3.3 Homo sapiens
-
-
-
1.4.3.3 Sus scrofa
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.4.3.3
-
 Homo sapiens
1.4.3.3
-
 Sus scrofa

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.4.3.3 astrocyte
-
 Homo sapiens
-
1.4.3.3 brain cortex
-
 Homo sapiens
-
1.4.3.3 kidney
-
 Sus scrofa
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.4.3.3 D-serine + H2O + O2
-
 Homo sapiens 2-oxo-3-hydroxypropionic acid + NH3 + H2O2
-
 ?
1.4.3.3 D-serine + H2O + O2
-
 Sus scrofa 2-oxo-3-hydroxypropionic acid + NH3 + H2O2
-
 ?

Subunits

EC Number Subunits Comment Organism
1.4.3.3 homodimer 2 * 40000, SDS-PAGE Homo sapiens
1.4.3.3 homodimer 2 * 40000, SDS-PAGE Sus scrofa

Synonyms

EC Number Synonyms Comment Organism
1.4.3.3 D-amino acid oxidase
-
 Homo sapiens
1.4.3.3 D-amino acid oxidase
-
 Sus scrofa
1.4.3.3 DAAO
-
 Homo sapiens
1.4.3.3 DAAO
-
 Sus scrofa

Cofactor

EC Number Cofactor Comment Organism Structure
1.4.3.3 FAD
-
 Homo sapiens
1.4.3.3 FAD
-
 Sus scrofa