EC Number | Crystallization (Comment) | Organism |
---|---|---|
1.11.1.24 | hanging drop vapour diffusion method with 100 mM citrate (pH 4.6) and 10% polyethylene glycol | Homo sapiens |
EC Number | Protein Variants | Comment | Organism |
---|---|---|---|
1.11.1.24 | C83S | increased activity compared to wild type Prx1 | Homo sapiens |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.11.1.24 | H2O2 | highly susceptible to inactivation by H2O2; highly susceptible to inactivation by H2O2 | Homo sapiens |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
1.11.1.24 | 43630 | - |
Prx2, Q-TOF mass spectrometry | Homo sapiens |
1.11.1.24 | 219700 | - |
Prx1, Q-TOF mass spectrometry | Homo sapiens |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.11.1.24 | Homo sapiens | P32119 | - |
- |
1.11.1.24 | Homo sapiens | Q06830 | - |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
1.11.1.24 | DEAE-Sepharose column chromatography, SP-Sepharose column chromatography, and Superdex 200 gel filtration | Homo sapiens |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.11.1.24 | H2O2 + reduced dithiothreitol | - |
Homo sapiens | H2O + oxidized dithiothreitol | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
1.11.1.24 | decamer | Prx1, X-ray crystallography | Homo sapiens |
1.11.1.24 | dimer | Prx2, X-ray crystallography | Homo sapiens |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.11.1.24 | peroxiredoxin 1 | - |
Homo sapiens |
1.11.1.24 | peroxiredoxin 2 | - |
Homo sapiens |
1.11.1.24 | Prx1 | - |
Homo sapiens |
1.11.1.24 | Prx2 | - |
Homo sapiens |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.11.1.24 | thioredoxin | - |
Homo sapiens |