EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
7.3.2.7 | ArsD | ArsD is an arsenic metallochaperone that delivers As(III) to the ArsA ATPase of the ArsAB pump, transferring the trivalent metalloids As(III) and Sb(III) to the ArsA subunit of the pump thereby increasing the affinity of ArsA for As(III), resulting in increased rates if extrusion and resistance to environmentally relevant concentrations of arsenite, mutational analysis of metalloid binding sites involved in As(III) transport and resistance, overview | Escherichia coli |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
7.3.2.7 | Mg2+ | - |
Escherichia coli |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
7.3.2.7 | ATP + H2O + arsenite/in | Escherichia coli | ArsA ATPase is the catalytic subunit of the ArsAB pump, ArsD is an arsenic chaperone to the ArsAB pump, transferring the trivalent metalloids As(III) and Sb(III) to the ArsA subunit of the pump thereby increasing the affinity of ArsA for As(III), resulting in increased rates if extrusion and resistance to environmentally relevant concentrations of arsenite | ADP + phosphate + arsenite/out | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
7.3.2.7 | Escherichia coli | - |
gene arsA encoded on the ars operon on plasmid R773 | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
7.3.2.7 | ATP + H2O + arsenite/in | ArsA ATPase is the catalytic subunit of the ArsAB pump, ArsD is an arsenic chaperone to the ArsAB pump, transferring the trivalent metalloids As(III) and Sb(III) to the ArsA subunit of the pump thereby increasing the affinity of ArsA for As(III), resulting in increased rates if extrusion and resistance to environmentally relevant concentrations of arsenite | Escherichia coli | ADP + phosphate + arsenite/out | - |
? | |
7.3.2.7 | ATP + H2O + arsenite/in | ArsA ATPase is the catalytic subunit of the ArsAB pump | Escherichia coli | ADP + phosphate + arsenite/out | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
7.3.2.7 | ArsAB | - |
Escherichia coli |
7.3.2.7 | As(III)-translocating ATPase | - |
Escherichia coli |