Literature summary extracted from

Muntjewerff, J.W.; Gellekink, H.; den Heijer, M.; Hoogendoorn, M.L.; Kahn, R.S.; Sinke, R.J.; Blom, H.J.
Polymorphisms in catechol-O-methyltransferase and methylenetetrahydrofolate reductase in relation to the risk of schizophrenia (2008), Eur. Neuropsychopharmacol., 18, 99-106.

Protein Variants

EC Number	Protein Variants	Comment	Organism
1.5.1.20	additional information	the C677T gene polymorphism in combination with catechol-O-methyltransferase G324A (Val108/158Met) polymorphism might increase schizophrenia susceptibility	Homo sapiens

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.5.1.20	Homo sapiens	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
1.5.1.20	lymphocyte	-	Homo sapiens	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.5.1.20	5,10-methylenetetrahydrofolate + reduced acceptor	-	Homo sapiens	5-methyltetrahydrofolate + oxidized acceptor	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
1.5.1.20	methylenetetrahydrofolate reductase	-	Homo sapiens
1.5.1.20	MTHFR	-	Homo sapiens

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Release 2023.1 (January 2023)