EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
3.5.3.1 | lipopolysaccharide | 0.001 mg/ml cause a 2fold increase in arginase activity and a marked increase in mRNA encoding arginase I | Rattus norvegicus |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.6.3.1 | apocynin | inhibition of NAD(P)H oxidase in alveolar macrophage by apocynin results in down-regulation of arginase activity and decrease in arginase I mRNA | Rattus norvegicus | |
3.5.3.1 | cycloheximide | inhibits protein synthesis | Rattus norvegicus | |
3.5.3.1 | additional information | ebselen does not inhibit arginase, apocynin does not affect the stability of arginase I mRNA but accelerates the decline of arginase activity when protein synthesis is inhibited by cycloheximide | Rattus norvegicus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.5.3.1 | L-arginine + H2O | Rattus norvegicus | - |
L-ornithine + urea | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.6.3.1 | Rattus norvegicus | - |
- |
- |
3.5.3.1 | Rattus norvegicus | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.6.3.1 | macrophage | alveolar macrophages. Inhibition of NAD(P)H oxidase by apocynin results in down-regulation of arginase | Rattus norvegicus | - |
3.5.3.1 | macrophage | alveolar macrophage | Rattus norvegicus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.5.3.1 | L-arginine + H2O | - |
Rattus norvegicus | L-ornithine + urea | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
3.5.3.1 | arginase I | - |
Rattus norvegicus |