Literature summary extracted from

Yamakoshi, Y.; Hu, J.C.; Fukae, M.; Yamakoshi, F.; Simmer, J.P.
How do enamelysin and kallikrein 4 process the 32-kDa enamelin? (2006), Eur. J. Oral Sci., 114 Suppl 1; 45-51; discussion 93-5, 379-80.

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.4.21.B12	Sus scrofa	-	-	-

Purification (Commentary)

EC Number	Purification (Comment)	Organism
3.4.21.B12	affinity purified	Sus scrofa

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
3.4.21.B12	enamel	from the hard enamel of developing pig teeth	Sus scrofa	-
3.4.21.B12	tooth	-	Sus scrofa	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
3.4.21.B12	32 kDa enamelin + H2O	five cleavage sites on the C-terminal sides of R180, Y205, H206, M219 and R262. Kallikrein 4 digestion of the 32 kDa enamelin generates nine major cleavage products. 12 h of digestion with KLK4, all of the 32 kDa enamelin has been cleaved. Some cleavage products persist after 48 h of digestion	Sus scrofa	?	-	?
3.4.21.B12	amelogenin + H2O	-	Sus scrofa	?	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
3.4.21.B12	kallikrein 4	-	Sus scrofa
3.4.21.B12	KLK4	-	Sus scrofa

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Release 2023.1 (January 2023)