EC Number | Cloned (Comment) | Organism |
---|---|---|
1.14.14.139 | genetic structure and phylogenetic analysis | Mus musculus |
1.14.14.139 | genetic structure and phylogenetic analysis | Homo sapiens |
1.14.14.139 | genetic structure and phylogenetic analysis | Rattus norvegicus |
1.14.14.139 | genetic structure and phylogenetic analysis | Sus scrofa |
1.14.14.139 | genetic structure and phylogenetic analysis | Oryctolagus cuniculus |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
1.14.14.139 | Fe2+ | a cytochrome P450 enzyme | Mus musculus | |
1.14.14.139 | Fe2+ | a cytochrome P450 enzyme | Homo sapiens | |
1.14.14.139 | Fe2+ | a cytochrome P450 enzyme | Rattus norvegicus | |
1.14.14.139 | Fe2+ | a cytochrome P450 enzyme | Sus scrofa | |
1.14.14.139 | Fe2+ | a cytochrome P450 enzyme | Oryctolagus cuniculus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.14.14.139 | 5beta-cholestan-3alpha,7alpha-diol + [reduced NADPH-hemoprotein reductase] + O2 | Mus musculus | - |
5beta-cholestan-3alpha,7alpha,12alpha-triol + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
1.14.14.139 | 5beta-cholestan-3alpha,7alpha-diol + [reduced NADPH-hemoprotein reductase] + O2 | Homo sapiens | - |
5beta-cholestan-3alpha,7alpha,12alpha-triol + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
1.14.14.139 | 5beta-cholestan-3alpha,7alpha-diol + [reduced NADPH-hemoprotein reductase] + O2 | Rattus norvegicus | - |
5beta-cholestan-3alpha,7alpha,12alpha-triol + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
1.14.14.139 | 5beta-cholestan-3alpha,7alpha-diol + [reduced NADPH-hemoprotein reductase] + O2 | Sus scrofa | - |
5beta-cholestan-3alpha,7alpha,12alpha-triol + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
1.14.14.139 | 5beta-cholestan-3alpha,7alpha-diol + [reduced NADPH-hemoprotein reductase] + O2 | Oryctolagus cuniculus | - |
5beta-cholestan-3alpha,7alpha,12alpha-triol + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
1.14.14.139 | additional information | Mus musculus | the enzyme is involved in trihydroxy bile acid metabolism and cholic acid synthesis from cholesterol, overview | ? | - |
? | |
1.14.14.139 | additional information | Homo sapiens | the enzyme is involved in trihydroxy bile acid metabolism and cholic acid synthesis from cholesterol, overview | ? | - |
? | |
1.14.14.139 | additional information | Rattus norvegicus | the enzyme is involved in trihydroxy bile acid metabolism and cholic acid synthesis from cholesterol, overview | ? | - |
? | |
1.14.14.139 | additional information | Sus scrofa | the enzyme is involved in trihydroxy bile acid metabolism and cholic acid synthesis from cholesterol, overview | ? | - |
? | |
1.14.14.139 | additional information | Oryctolagus cuniculus | the enzyme is involved in trihydroxy bile acid metabolism and cholic acid synthesis from cholesterol, overview | ? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.14.14.139 | Homo sapiens | - |
- |
- |
1.14.14.139 | Mus musculus | - |
- |
- |
1.14.14.139 | Oryctolagus cuniculus | - |
- |
- |
1.14.14.139 | Rattus norvegicus | - |
- |
- |
1.14.14.139 | Sus scrofa | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.14.14.139 | 5beta-cholestan-3alpha,7alpha-diol + [reduced NADPH-hemoprotein reductase] + O2 | - |
Mus musculus | 5beta-cholestan-3alpha,7alpha,12alpha-triol + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
1.14.14.139 | 5beta-cholestan-3alpha,7alpha-diol + [reduced NADPH-hemoprotein reductase] + O2 | - |
Homo sapiens | 5beta-cholestan-3alpha,7alpha,12alpha-triol + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
1.14.14.139 | 5beta-cholestan-3alpha,7alpha-diol + [reduced NADPH-hemoprotein reductase] + O2 | - |
Rattus norvegicus | 5beta-cholestan-3alpha,7alpha,12alpha-triol + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
1.14.14.139 | 5beta-cholestan-3alpha,7alpha-diol + [reduced NADPH-hemoprotein reductase] + O2 | - |
Sus scrofa | 5beta-cholestan-3alpha,7alpha,12alpha-triol + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
1.14.14.139 | 5beta-cholestan-3alpha,7alpha-diol + [reduced NADPH-hemoprotein reductase] + O2 | - |
Oryctolagus cuniculus | 5beta-cholestan-3alpha,7alpha,12alpha-triol + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
1.14.14.139 | additional information | the enzyme is involved in trihydroxy bile acid metabolism and cholic acid synthesis from cholesterol, overview | Mus musculus | ? | - |
? | |
1.14.14.139 | additional information | the enzyme is involved in trihydroxy bile acid metabolism and cholic acid synthesis from cholesterol, overview | Homo sapiens | ? | - |
? | |
1.14.14.139 | additional information | the enzyme is involved in trihydroxy bile acid metabolism and cholic acid synthesis from cholesterol, overview | Rattus norvegicus | ? | - |
? | |
1.14.14.139 | additional information | the enzyme is involved in trihydroxy bile acid metabolism and cholic acid synthesis from cholesterol, overview | Sus scrofa | ? | - |
? | |
1.14.14.139 | additional information | the enzyme is involved in trihydroxy bile acid metabolism and cholic acid synthesis from cholesterol, overview | Oryctolagus cuniculus | ? | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.14.14.139 | CYP8B1 | - |
Mus musculus |
1.14.14.139 | CYP8B1 | - |
Homo sapiens |
1.14.14.139 | CYP8B1 | - |
Rattus norvegicus |
1.14.14.139 | CYP8B1 | - |
Sus scrofa |
1.14.14.139 | CYP8B1 | - |
Oryctolagus cuniculus |
1.14.14.139 | More | the enzyme belongs to the CYP8B subfamily | Mus musculus |
1.14.14.139 | More | the enzyme belongs to the CYP8B subfamily | Homo sapiens |
1.14.14.139 | More | the enzyme belongs to the CYP8B subfamily | Rattus norvegicus |
1.14.14.139 | More | the enzyme belongs to the CYP8B subfamily | Sus scrofa |
1.14.14.139 | More | the enzyme belongs to the CYP8B subfamily | Oryctolagus cuniculus |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.14.14.139 | cytochrome | a cytochrome P450 enzyme | Rattus norvegicus | |
1.14.14.139 | cytochrome | a cytochrome P450 enzyme | Oryctolagus cuniculus | |
1.14.14.139 | cytochrome P450 | a cytochrome P450 enzyme | Mus musculus | |
1.14.14.139 | cytochrome P450 | a cytochrome P450 enzyme | Homo sapiens | |
1.14.14.139 | cytochrome P450 | a cytochrome P450 enzyme | Sus scrofa |