EC Number | Crystallization (Comment) | Organism |
---|---|---|
1.3.1.20 | - |
Macaca fascicularis |
EC Number | Protein Variants | Comment | Organism |
---|---|---|---|
1.3.1.20 | F279A | the mutation affects inhibition and substrate affinity | Macaca fascicularis |
1.3.1.20 | K97M | mutant shows almost complete abrogation in activity for D-xylose oxidation and NADP+, and very poor activity with camphorquinone reduction and NADPH | Macaca fascicularis |
1.3.1.20 | K97R | mutant shows almost complete abrogation in activity for D-xylose oxidation and NADP+, and very poor activity with camphorquinone reduction and NADPH | Macaca fascicularis |
1.3.1.20 | W125A | the mutation affects inhibition and substrate affinity | Macaca fascicularis |
1.3.1.20 | W254A | the mutation affects inhibition and substrate affinity | Macaca fascicularis |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.3.1.20 | 2,6-dihydroxyanthraquinone | competitive inhibitor | Macaca fascicularis | |
1.3.1.20 | 2,6-dihydroxyanthraquinone | competitive inhibitor | Sus scrofa | |
1.3.1.20 | 4-hydroxyacetophenone | competitive inhibitor | Macaca fascicularis | |
1.3.1.20 | 4-hydroxyacetophenone | competitive inhibitor | Sus scrofa | |
1.3.1.20 | isoascorbic acid | competitive inhibitor | Macaca fascicularis | |
1.3.1.20 | isoascorbic acid | competitive inhibitor | Sus scrofa | |
1.3.1.20 | L-ascorbic acid | competitive inhibitor | Macaca fascicularis | |
1.3.1.20 | L-ascorbic acid | competitive inhibitor | Sus scrofa |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
1.3.1.20 | Mg2+ | activates | Sus scrofa | |
1.3.1.20 | Mg2+ | activates | Macaca fascicularis |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.3.1.20 | Bos taurus | Q148L6 | - |
- |
1.3.1.20 | Macaca fascicularis | - |
- |
- |
1.3.1.20 | Mus musculus | Q9DBB8 | - |
- |
1.3.1.20 | Pongo abelii | Q5R5J5 | - |
- |
1.3.1.20 | Sus scrofa | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.3.1.20 | kidney | - |
Macaca fascicularis | - |
1.3.1.20 | lens | - |
Mus musculus | - |
1.3.1.20 | additional information | not found in liver and kidney | Mus musculus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.3.1.20 | camphorquinone + NAD(P)H | - |
Sus scrofa | (1R)-1,7,7-trimethylbicyclo[2.2.1]heptane-2,3-diol + NADP+ | - |
? | |
1.3.1.20 | camphorquinone + NAD(P)H | - |
Macaca fascicularis | (1R)-1,7,7-trimethylbicyclo[2.2.1]heptane-2,3-diol + NADP+ | - |
? | |
1.3.1.20 | camphorquinone + NAD(P)H | - |
Mus musculus | (1R)-1,7,7-trimethylbicyclo[2.2.1]heptane-2,3-diol + NADP+ | - |
? | |
1.3.1.20 | camphorquinone + NAD(P)H | - |
Pongo abelii | (1R)-1,7,7-trimethylbicyclo[2.2.1]heptane-2,3-diol + NADP+ | - |
? | |
1.3.1.20 | camphorquinone + NAD(P)H | - |
Bos taurus | (1R)-1,7,7-trimethylbicyclo[2.2.1]heptane-2,3-diol + NADP+ | - |
? | |
1.3.1.20 | D-xylose + NADP+ | - |
Sus scrofa | D-xylono-1,5-lactone + NADPH + H+ | - |
? | |
1.3.1.20 | D-xylose + NADP+ | - |
Macaca fascicularis | D-xylono-1,5-lactone + NADPH + H+ | - |
? | |
1.3.1.20 | D-xylose + NADP+ | - |
Mus musculus | D-xylono-1,5-lactone + NADPH + H+ | - |
? | |
1.3.1.20 | D-xylose + NADP+ | - |
Pongo abelii | D-xylono-1,5-lactone + NADPH + H+ | - |
? | |
1.3.1.20 | D-xylose + NADP+ | - |
Bos taurus | D-xylono-1,5-lactone + NADPH + H+ | - |
? | |
1.3.1.20 | trans-1,2-dihydrobenzene-1,2-diol + NAD(P)+ | - |
Sus scrofa | catechol + NAD(P)H | the reaction produces a ketol which then enolizes to the catechol | ? | |
1.3.1.20 | trans-1,2-dihydrobenzene-1,2-diol + NAD(P)+ | - |
Macaca fascicularis | catechol + NAD(P)H | the reaction produces a ketol which then enolizes to the catechol | ? | |
1.3.1.20 | trans-1,2-dihydrobenzene-1,2-diol + NAD(P)+ | - |
Mus musculus | catechol + NAD(P)H | the reaction produces a ketol which then enolizes to the catechol | ? | |
1.3.1.20 | trans-1,2-dihydrobenzene-1,2-diol + NAD(P)+ | - |
Pongo abelii | catechol + NAD(P)H | the reaction produces a ketol which then enolizes to the catechol | ? | |
1.3.1.20 | trans-1,2-dihydrobenzene-1,2-diol + NAD(P)+ | - |
Bos taurus | catechol + NAD(P)H | the reaction produces a ketol which then enolizes to the catechol | ? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
1.3.1.20 | dimer | x-ray crystallography | Sus scrofa |
1.3.1.20 | dimer | x-ray crystallography | Macaca fascicularis |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.3.1.20 | DHDH | - |
Sus scrofa |
1.3.1.20 | DHDH | - |
Macaca fascicularis |
1.3.1.20 | DHDH | - |
Mus musculus |
1.3.1.20 | DHDH | - |
Pongo abelii |
1.3.1.20 | DHDH | - |
Bos taurus |
1.3.1.20 | dihydrodiol dehydrogenase | - |
Sus scrofa |
1.3.1.20 | dihydrodiol dehydrogenase | - |
Macaca fascicularis |
1.3.1.20 | dihydrodiol dehydrogenase | - |
Mus musculus |
1.3.1.20 | dihydrodiol dehydrogenase | - |
Pongo abelii |
1.3.1.20 | dihydrodiol dehydrogenase | - |
Bos taurus |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.3.1.20 | NAD+ | - |
Sus scrofa | |
1.3.1.20 | NAD+ | - |
Macaca fascicularis | |
1.3.1.20 | NAD+ | - |
Mus musculus | |
1.3.1.20 | NAD+ | - |
Pongo abelii | |
1.3.1.20 | NAD+ | - |
Bos taurus | |
1.3.1.20 | NADP+ | dependent on | Sus scrofa | |
1.3.1.20 | NADP+ | dependent on | Macaca fascicularis | |
1.3.1.20 | NADP+ | dependent on | Mus musculus | |
1.3.1.20 | NADP+ | dependent on | Pongo abelii | |
1.3.1.20 | NADP+ | dependent on | Bos taurus |
EC Number | IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|---|
1.3.1.20 | 0.043 | - |
- |
Sus scrofa | isoascorbic acid | |
1.3.1.20 | 0.45 | - |
- |
Sus scrofa | L-ascorbic acid |