Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Sun, D.F.; Weng, Y.R.; Chen, Y.X.; Lu, R.; Wang, X.; Fang, J.Y.
    Knock-down of methylenetetrahydrofolate reductase reduces gastric cancer cell survival: An in vitro study (2008), Cell Biol. Int., 32, 879-887.
    View publication on PubMed

Application

EC Number Application Comment Organism
1.5.1.20 medicine MTHFR inhibition may be a novel anticancer approach Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.5.1.20 additional information inhibiting MTHFR with either antisense or siRNA decreases the viability of methionine-dependent transformed gastric cancer cells Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
1.5.1.20 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.5.1.20 MKN-45 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.5.1.20 5,10-methylenetetrahydrofolate + reduced acceptor
-
 Homo sapiens 5-methyltetrahydrofolate + oxidized acceptor
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.5.1.20 methylenetetrahydrofolate reductase
-
 Homo sapiens
1.5.1.20 MTHFR
-
 Homo sapiens