EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.7.1.20 | 2',3',5'-tri-O-acetyl-adenosine | 10-90% inhibition at 0.1 mM | Mycobacterium tuberculosis | |
2.7.1.20 | 2'-deoxy-2,2'-difluoro-adenosine | 10-90% inhibition at 0.1 mM | Mycobacterium tuberculosis | |
2.7.1.20 | 2'-deoxy-adenosine | 10-90% inhibition at 0.1 mM | Mycobacterium tuberculosis | |
2.7.1.20 | 2'-O-methyl-adenosine | 10-90% inhibition at 0.1 mM | Mycobacterium tuberculosis | |
2.7.1.20 | 2-chloro-2'-deoxy-2'-fluoro-9-[beta-D-arabinofuranosyl]-adenine | 10-90% inhibition at 0.1 mM | Mycobacterium tuberculosis | |
2.7.1.20 | 2-chloro-2'-deoxy-2'-fluoro-adenosine | 10-90% inhibition at 0.01 mM | Mycobacterium tuberculosis | |
2.7.1.20 | 2-chloro-2'-deoxy-adenosine | 10-90% inhibition at 0.1 mM | Mycobacterium tuberculosis | |
2.7.1.20 | 2-chloro-4'-thio-adenosine | 10-90% inhibition at 0.1 mM | Mycobacterium tuberculosis | |
2.7.1.20 | 2-chloro-adenosine | 10-90% inhibition at 0.01 mM | Mycobacterium tuberculosis | |
2.7.1.20 | 2-fluoro-9-[beta-D-arabinofuranosyl]-adenine | 10-90% inhibition at 0.1 mM | Mycobacterium tuberculosis | |
2.7.1.20 | 2-fluoro-adenosine | 10-90% inhibition at 0.1 mM | Homo sapiens | |
2.7.1.20 | 2-fluoro-adenosine | 10-90% inhibition at 0.001 mM, competitive inhibitor | Mycobacterium tuberculosis | |
2.7.1.20 | 2-methyl-adenosine | 10-90% inhibition at 0.1 mM | Mycobacterium tuberculosis | |
2.7.1.20 | 3'-deoxy-3'-azido-adenosine | 10-90% inhibition at 0.1 mM | Homo sapiens | |
2.7.1.20 | 3-[beta-D-ribofuranosyl]-adenine | 10-90% inhibition at 0.01 mM | Mycobacterium tuberculosis | |
2.7.1.20 | 5'-amino-5'-deoxy-adenosine | 10-90% inhibition at 0.001 mM | Homo sapiens | |
2.7.1.20 | 5'-amino-5'-deoxy-adenosine | 10-90% inhibition at 0.001 mM, competitive inhibitor | Mycobacterium tuberculosis | |
2.7.1.20 | 5'-carboxamido-adenosine | 10-90% inhibition at 0.1 mM | Mycobacterium tuberculosis | |
2.7.1.20 | 5'-deoxy-adenosine | 10-90% inhibition at 0.01 mM | Mycobacterium tuberculosis | |
2.7.1.20 | 6-methyl-purine riboside | 10-90% inhibition at 0.01 mM | Mycobacterium tuberculosis | |
2.7.1.20 | 7-deaza-carbocyclic-adenosine | 10-90% inhibition at 0.1 mM | Mycobacterium tuberculosis | |
2.7.1.20 | 7-[alpha-D-arabinofuranosyl]-adenine | 10-90% inhibition at 0.1 mM | Mycobacterium tuberculosis | |
2.7.1.20 | 7-[alpha-D-ribofuranosyl]-adenine | 10-90% inhibition at 0.1 mM | Mycobacterium tuberculosis | |
2.7.1.20 | 8-aza-2'-deoxy-adenosine | 10-90% inhibition at 0.1 mM | Mycobacterium tuberculosis | |
2.7.1.20 | 8-aza-8-[beta-D-ribofuranosyl]-adenine | 10-90% inhibition at 0.1 mM | Mycobacterium tuberculosis | |
2.7.1.20 | 8-aza-adenosine | 10-90% inhibition at 0.01 mM, competitive inhibitor | Mycobacterium tuberculosis | |
2.7.1.20 | 8-aza-carbocyclic-adenosine | 10-90% inhibition at 0.1 mM | Homo sapiens | |
2.7.1.20 | 8-aza-carbocyclic-adenosine | 10-90% inhibition at 0.1 mM | Mycobacterium tuberculosis | |
2.7.1.20 | 9-(2-deoxy-beta-D-erythropentopyranosyl)-adenine | 10-90% inhibition at 0.1 mM | Mycobacterium tuberculosis | |
2.7.1.20 | 9-[alpha-D-ribofuranosyl]-adenine | 10-90% inhibition at 0.1 mM | Mycobacterium tuberculosis | |
2.7.1.20 | 9-[alpha-L-lyxofuranosyl]-2-fluoro-adenine | 10-90% inhibition at 0.1 mM | Mycobacterium tuberculosis | |
2.7.1.20 | 9-[alpha-L-lyxofuranosyl]-adenine | 10-90% inhibition at 0.1 mM | Mycobacterium tuberculosis | |
2.7.1.20 | 9-[beta-D-5-methyl-(allo)-ribofuranosyl]-2-fluoro-adenine | 10-90% inhibition at 0.01 mM | Mycobacterium tuberculosis | |
2.7.1.20 | 9-[beta-D-5-methyl-(allo)-ribofuranosyl]-6-methyl-purine | 10-90% inhibition at 0.01 mM | Mycobacterium tuberculosis | |
2.7.1.20 | 9-[beta-D-5-methyl-(talo)-ribofuranosyl]-2-fluoro-adenine | 10-90% inhibition at 0.1 mM | Mycobacterium tuberculosis | |
2.7.1.20 | 9-[beta-D-5-methyl-(talo)-ribofuranosyl]-6-methyl-purine | 10-90% inhibition at 0.1 mM | Mycobacterium tuberculosis | |
2.7.1.20 | aristeromycin | 10-90% inhibition at 0.1 mM | Mycobacterium tuberculosis |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.7.1.20 | Homo sapiens | - |
- |
- |
2.7.1.20 | Mycobacterium tuberculosis | P9WID5 | - |
- |
2.7.1.20 | Mycobacterium tuberculosis H37Rv | P9WID5 | - |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.1.20 | ATP + 2'-deoxy-2,2'-difluoro-adenosine | 0.5% of the activity with adenosine | Mycobacterium tuberculosis | ADP + 2'-deoxy-2,2'-difluoro-AMP | - |
? | |
2.7.1.20 | ATP + 2'-deoxy-2,2'-difluoro-adenosine | 0.5% of the activity with adenosine | Mycobacterium tuberculosis H37Rv | ADP + 2'-deoxy-2,2'-difluoro-AMP | - |
? | |
2.7.1.20 | ATP + 2'-deoxy-adenosine | 3% of the activity with adenosine | Homo sapiens | ? | - |
? | |
2.7.1.20 | ATP + 2'-deoxy-adenosine | 0.3% of the activity with adenosine | Mycobacterium tuberculosis | ADP + 2'-deoxy-AMP | - |
? | |
2.7.1.20 | ATP + 2'-deoxy-adenosine | 0.3% of the activity with adenosine | Mycobacterium tuberculosis H37Rv | ADP + 2'-deoxy-AMP | - |
? | |
2.7.1.20 | ATP + 2-amino-carbocyclic-adenosine | 35.8% of the activity with adenosine | Homo sapiens | ? | - |
? | |
2.7.1.20 | ATP + 2-amino-carbocyclic-adenosine | 0.4% of the activity with adenosine | Mycobacterium tuberculosis | ADP + 2-amino-carbocyclic-AMP | - |
? | |
2.7.1.20 | ATP + 2-amino-carbocyclic-adenosine | 0.4% of the activity with adenosine | Mycobacterium tuberculosis H37Rv | ADP + 2-amino-carbocyclic-AMP | - |
? | |
2.7.1.20 | ATP + 2-chloro-adenosine | 0.7% of the activity with adenosine | Homo sapiens | ? | - |
? | |
2.7.1.20 | ATP + 2-chloro-adenosine | 11.5% of the activity with adenosine | Mycobacterium tuberculosis | ADP + 2-chloro-AMP | - |
? | |
2.7.1.20 | ATP + 2-chloro-adenosine | 11.5% of the activity with adenosine | Mycobacterium tuberculosis H37Rv | ADP + 2-chloro-AMP | - |
? | |
2.7.1.20 | ATP + 2-fluoro-9-[beta-D-arabinofuranosyl]-adenine | 0.9% of the activity with adenosine | Mycobacterium tuberculosis | ADP + 2-fluoro-9-[beta-D-arabinofuranosyl]-AMP | - |
? | |
2.7.1.20 | ATP + 2-fluoro-adenosine | 75% of the activity with adenosine | Homo sapiens | ? | - |
? | |
2.7.1.20 | ATP + 2-fluoro-adenosine | 52% of the activity with adenosine | Mycobacterium tuberculosis | ADP + 2-fluoro-AMP | - |
? | |
2.7.1.20 | ATP + 2-methyl-adenosine | 0.14% of the activity with adenosine | Homo sapiens | ? | - |
? | |
2.7.1.20 | ATP + 2-methyl-adenosine | 2% of the activity with adenosine | Mycobacterium tuberculosis | ADP + 2-methyl-AMP | - |
? | |
2.7.1.20 | ATP + 3-[beta-D-ribofuranosyl]-adenine | 11.2% of the activity with adenosine | Homo sapiens | ? | - |
? | |
2.7.1.20 | ATP + 3-[beta-D-ribofuranosyl]-adenine | 0.7% of the activity with adenosine | Mycobacterium tuberculosis | ADP + 3-[beta-D-ribofuranosyl]-AMP | - |
? | |
2.7.1.20 | ATP + 6-methyl-purine riboside | 41% of the activity with adenosine | Homo sapiens | ? | - |
? | |
2.7.1.20 | ATP + 6-methyl-purine riboside | 2.75% of the activity with adenosine | Mycobacterium tuberculosis | ADP + 6-methylpurine-D-riboside 5'-phosphate | - |
? | |
2.7.1.20 | ATP + 8-aza-adenosine | 38% of the activity with adenosine | Homo sapiens | ? | - |
? | |
2.7.1.20 | ATP + 8-aza-adenosine | 4% of the activity with adenosine | Mycobacterium tuberculosis | ADP + 8-aza-AMP | - |
? | |
2.7.1.20 | ATP + 8-aza-carbocyclic-adenosine | 26% of the activity with adenosine | Homo sapiens | ? | - |
? | |
2.7.1.20 | ATP + 8-aza-carbocyclic-adenosine | 4% of the activity with adenosine | Mycobacterium tuberculosis | ADP + 8-aza-carbocyclic-AMP | - |
? | |
2.7.1.20 | ATP + 9-[alpha-L-lyxofuranosyl]-2-fluoro-adenine | 3.3% of the activity with adenosine | Mycobacterium tuberculosis | ADP + 9-[alpha-L-lyxofuranosyl]-2-fluoro-AMP | - |
? | |
2.7.1.20 | ATP + 9-[alpha-L-lyxofuranosyl]-adenine | 15% of the activity with adenosine | Homo sapiens | ? | - |
? | |
2.7.1.20 | ATP + 9-[alpha-L-lyxofuranosyl]-adenine | 3.8% of the activity with adenosine | Mycobacterium tuberculosis | ADP + 9-[alpha-L-lyxofuranosyl]-AMP | - |
? | |
2.7.1.20 | ATP + 9-[beta-D-5-methyl-(allo)-ribofuranosyl]-2-fluoro-adenine | 0.1% of the activity with adenosine | Mycobacterium tuberculosis | ADP + 9-[beta-D-5-methyl-(allo)-ribofuranosyl]-2-fluoro-AMP | - |
? | |
2.7.1.20 | ATP + 9-[beta-D-arabinofuranosyl]-adenine | 0.25% of the activity with adenosine | Homo sapiens | ? | - |
? | |
2.7.1.20 | ATP + 9-[beta-D-arabinofuranosyl]-adenine | 0.6% of the activity with adenosine | Mycobacterium tuberculosis | ADP + 9-[beta-D-arabinofuranosyl]-adenine 5'-phosphate | - |
? | |
2.7.1.20 | ATP + adenosine | - |
Homo sapiens | ADP + AMP | - |
? | |
2.7.1.20 | ATP + adenosine | - |
Mycobacterium tuberculosis | ADP + AMP | - |
? | |
2.7.1.20 | ATP + adenosine | - |
Mycobacterium tuberculosis H37Rv | ADP + AMP | - |
? | |
2.7.1.20 | ATP + aristeromycin | 37% of the activity with adenosine | Homo sapiens | ? | - |
? | |
2.7.1.20 | ATP + aristeromycin | 37.5% of the activity with adenosine | Mycobacterium tuberculosis | ADP + aristeromycin 5'-phosphate | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.7.1.20 | Ado kinase | - |
Homo sapiens |
2.7.1.20 | Ado kinase | - |
Mycobacterium tuberculosis |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.7.1.20 | 0.0005 | - |
2-fluoro-adenosine | - |
Mycobacterium tuberculosis | |
2.7.1.20 | 0.0008 | - |
5'-amino-5'-deoxy-adenosine | - |
Mycobacterium tuberculosis |