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Literature summary extracted from

  • Baron, R.A.; Seabra, M.C.
    Rab geranylgeranylation occurs preferentially via the pre-formed REP-RGGT complex and is regulated by geranylgeranyl pyrophosphate (2008), Biochem. J., 415, 67-75.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.5.1.60 Rab escort protein RGGT increases the ability of Rab escort protein to extract endogenous prenylated Rabs from membranes in vitro by stabilizing a soluble Rab escort protein-RGGT-geranylgeranylated Rab complex Homo sapiens

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.5.1.60 expressed in Sf9 cells Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
2.5.1.60 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.5.1.60 nickel-Sepharose affinity chromatography Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.5.1.60 geranylgeranyl diphosphate + protein-cysteine
-
 Homo sapiens S-geranylgeranyl-protein + diphosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.5.1.60 Rab geranylgeranyl transferase
-
 Homo sapiens
2.5.1.60 RGGT
-
 Homo sapiens