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Literature summary extracted from

  • Mar-Heyming, R.; Miyazaki, M.; Weissglas-Volkov, D.; Kolaitis, N.A.; Sadaat, N.; Plaisier, C.; Pajukanta, P.; Cantor, R.M.; de Bruin, T.W.; Ntambi, J.M.; Lusis, A.J.
    Association of stearoyl-CoA desaturase 1 activity with familial combined hyperlipidemia (2008), Arterioscler. Thromb. Vasc. Biol., 28, 1193-1199.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.19.1 stearoyl-CoA + ferrocytochrome b5 + O2 + H+ Homo sapiens rate-limiting enzyme involved in the synthesis of monounsaturated fatty acids, it is also involved in familial combined hyperlipidemia, fatty acid desaturation index, overview oleoyl-CoA + ferricytochrome b5 + H2O
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.14.19.1 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.19.1 stearoyl-CoA + ferrocytochrome b5 + O2 + H+
-
 Homo sapiens oleoyl-CoA + ferricytochrome b5 + H2O
-
 ?
1.14.19.1 stearoyl-CoA + ferrocytochrome b5 + O2 + H+ rate-limiting enzyme involved in the synthesis of monounsaturated fatty acids, it is also involved in familial combined hyperlipidemia, fatty acid desaturation index, overview Homo sapiens oleoyl-CoA + ferricytochrome b5 + H2O
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.14.19.1 SCD1
-
 Homo sapiens
1.14.19.1 stearoyl-CoA desaturase 1
-
 Homo sapiens

Cofactor

EC Number Cofactor Comment Organism Structure
1.14.19.1 ferrocytochrome b5
-
 Homo sapiens