Literature summary extracted from

Buszman, E.; Wrzesniok, D.; Surazynski, A.; Patka, J.; Moleda, K.
Effect of melanin on netilmicin-induced inhibition of collagen biosynthesis in human skin fibroblasts (2006), Bioorg. Med. Chem., 14, 8155-8161.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
3.4.13.9	melanin	30% inhibition at 0.1 mg/ml, reverses inhibition of prolidase by netilmicin	Homo sapiens
3.4.13.9	netilmicin	80% inhibition at 0.01 mM, reversible by melanin	Homo sapiens

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.4.13.9	Homo sapiens	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
3.4.13.9	fibroblast	-	Homo sapiens	-
3.4.13.9	skin	-	Homo sapiens	-

Synonyms

EC Number	Synonyms	Comment	Organism
3.4.13.9	prolidase	-	Homo sapiens

IC50 Value

EC Number	IC50 Value	IC50 Value Maximum	Comment	Organism	Inhibitor	Structure
3.4.13.9	0.005	-	-	Homo sapiens	netilmicin

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Release 2023.1 (January 2023)