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Literature summary extracted from

  • Lam, S.H.; Chen, J.M.; Kang, C.J.; Chen, C.H.; Lee, S.S.
    alpha-Glucosidase inhibitors from the seeds of Syagrus romanzoffiana (2008), Phytochemistry, 69, 1173-1178.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.2.1.20 13-hydroxykompasinol A isolated from seeds of Syagrus romanzoffiana Geobacillus stearothermophilus
3.2.1.20 3,3',4,5,5'-pentahydroxy-trans-stilbene isolated from seeds of Syagrus romanzoffiana Geobacillus stearothermophilus
3.2.1.20 4-hydroxybenzoic acid isolated from seeds of Syagrus romanzoffiana Geobacillus stearothermophilus
3.2.1.20 kompasinol A isolated from seeds of Syagrus romanzoffiana Geobacillus stearothermophilus
3.2.1.20 additional information defatted EtOH extract of the seeds of Syagrus romanzoffiana shows 55% inhibitory activity against alpha-glucosidase at a concentration of 0.010 mg/ml, inhibitor structure determination by NMR, overview Geobacillus stearothermophilus
3.2.1.20 piceatannol isolated from seeds of Syagrus romanzoffiana Geobacillus stearothermophilus
3.2.1.20 resveratrol isolated from seeds of Syagrus romanzoffiana Geobacillus stearothermophilus
3.2.1.20 scirpusin A isolated from seeds of Syagrus romanzoffiana Geobacillus stearothermophilus
3.2.1.20 scirpusin C isolated from seeds of Syagrus romanzoffiana Geobacillus stearothermophilus

Organism

EC Number Organism UniProt Comment Textmining
3.2.1.20 Geobacillus stearothermophilus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.2.1.20 commercial preparation
-
 Geobacillus stearothermophilus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.2.1.20 4-nitrophenyl alpha-D-glucopyranoside + H2O
-
 Geobacillus stearothermophilus 4-nitrophenol + alpha-D-glucose
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.2.1.20 alpha-glucosidase type IV
-
 Geobacillus stearothermophilus

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.2.1.20 37
-
 assay at Geobacillus stearothermophilus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.2.1.20 6.5
-
 assay at Geobacillus stearothermophilus

IC50 Value

EC Number IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
3.2.1.20 0.0049
-
 pH 6.5, 37°C Geobacillus stearothermophilus scirpusin C
3.2.1.20 0.0065
-
 pH 6.5, 37°C Geobacillus stearothermophilus 13-hydroxykompasinol A
3.2.1.20 0.0083
-
 pH 6.5, 37°C Geobacillus stearothermophilus scirpusin A
3.2.1.20 0.0112
-
 pH 6.5, 37°C Geobacillus stearothermophilus kompasinol A
3.2.1.20 0.0192
-
 pH 6.5, 37°C Geobacillus stearothermophilus 3,3',4,5,5'-pentahydroxy-trans-stilbene
3.2.1.20 0.0232
-
 pH 6.5, 37°C Geobacillus stearothermophilus piceatannol
3.2.1.20 0.0239
-
 pH 6.5, 37°C Geobacillus stearothermophilus resveratrol
3.2.1.20 0.0564
-
 pH 6.5, 37°C Geobacillus stearothermophilus 4-hydroxybenzoic acid