Any feedback?
Literature summary extracted from
- Identification and enzymatic activities of four protein disulfide isomerase (PDI) isoforms of Leishmania amazonensis (2007), Parasitol. Res., 102, 437-446.
Activating Compound
| EC Number | Activating Compound | Comment | Organism | Structure |
|---|---|---|---|---|
| 5.3.4.1 | cCMP | - |
Leishmania amazonensis |  |
| 5.3.4.1 | GSH | - |
Leishmania amazonensis | |
| 5.3.4.1 | GSSG | - |
Leishmania amazonensis | |
Cloned(Commentary)
| EC Number | Cloned (Comment) | Organism |
|---|---|---|
| 5.3.4.1 | isozyme pdi-15, DNA and amino acid sequence determination and analysis, sequence comparison with other Leishmania species, overview | Leishmania amazonensis |
| 5.3.4.1 | isozyme pdi-40, DNA and amino acid sequence determination and analysis, sequence comparison with other Leishmania species, overview | Leishmania amazonensis |
| 5.3.4.1 | isozyme pdi-47, DNA and amino acid sequence determination and analysis, sequence comparison with other Leishmania species, overview | Leishmania amazonensis |
| 5.3.4.1 | isozyme pdi-52, DNA and amino acid sequence determination and analysis, sequence comparison with other Leishmania species, overview | Leishmania amazonensis |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 5.3.4.1 | 4-chloromercuribenzoic acid | - |
Leishmania amazonensis | |
| 5.3.4.1 | bacitracin | - |
Leishmania amazonensis | |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 5.3.4.1 | additional information | - |
additional information | kinetics | Leishmania amazonensis |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 5.3.4.1 | 15000 | - |
x * 15000, isozyme pdi-15, SDS-PAGE | Leishmania amazonensis |
| 5.3.4.1 | 40000 | - |
x * 40000, isozyme pdi-40, SDS-PAGE | Leishmania amazonensis |
| 5.3.4.1 | 47000 | - |
x * 47000, isozyme pdi-47, SDS-PAGE | Leishmania amazonensis |
| 5.3.4.1 | 52000 | - |
x * 52000, isozyme pdi-52, SDS-PAGE | Leishmania amazonensis |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 5.3.4.1 | Leishmania amazonensis | A7YBW7 | 52 kDa isozyme | - |
| 5.3.4.1 | Leishmania amazonensis | A7YBX0 | 47 kDa isozyme, fragment | - |
| 5.3.4.1 | Leishmania amazonensis | A7YBX2 | 40 kDa isozyme, fragment | - |
| 5.3.4.1 | Leishmania amazonensis | A7YBX4 | 15 kDa isozyme, fragment | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 5.3.4.1 | insulin | - |
Leishmania amazonensis | ? | - |
? | |
| 5.3.4.1 | scrambled RNAse | - |
Leishmania amazonensis | ? | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 5.3.4.1 | ? | x * 15000, isozyme pdi-15, SDS-PAGE | Leishmania amazonensis |
| 5.3.4.1 | ? | x * 40000, isozyme pdi-40, SDS-PAGE | Leishmania amazonensis |
| 5.3.4.1 | ? | x * 47000, isozyme pdi-47, SDS-PAGE | Leishmania amazonensis |
| 5.3.4.1 | ? | x * 52000, isozyme pdi-52, SDS-PAGE | Leishmania amazonensis |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 5.3.4.1 | PDI | - |
Leishmania amazonensis |
| 5.3.4.1 | pdi-15 | - |
Leishmania amazonensis |
| 5.3.4.1 | pdi-40 | - |
Leishmania amazonensis |
| 5.3.4.1 | pdi-47 | - |
Leishmania amazonensis |
| 5.3.4.1 | pdi-52 | - |
Leishmania amazonensis |
| 5.3.4.1 | protein-disulfide isomerase | - |
Leishmania amazonensis |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 5.3.4.1 | 8 | - |
assay at | Leishmania amazonensis |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
