Literature summary extracted from

Yau, S.; Wachsman, J.T.
The Bacillus megaterium ribonucleotide reductase: evidence for a B 12 coenzyme requirement (1973), Mol. Cell. Biochem., 1, 101-105.

Activating Compound

EC Number	Activating Compound	Comment	Organism	Structure
1.17.4.2	ATP	required	Priestia megaterium

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
1.17.4.2	Hydroxyurea	20 mM, 20% inhibition	Priestia megaterium

Metals/Ions

EC Number	Metals/Ions	Comment	Organism	Structure
1.17.4.2	Mg2+	required	Priestia megaterium

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.17.4.2	Priestia megaterium	-	-	-
1.17.4.2	Priestia megaterium KM / ATCC 13632	-	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.17.4.2	CDP + reduced dithiothreitol	-	Priestia megaterium	dCDP + oxidized dithiothreitol + H2O	-	?
1.17.4.2	CDP + reduced dithiothreitol	-	Priestia megaterium KM / ATCC 13632	dCDP + oxidized dithiothreitol + H2O	-	?

Cofactor

EC Number	Cofactor	Comment	Organism	Structure
1.17.4.2	coenzyme B12	required	Priestia megaterium

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Release 2023.1 (January 2023)