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Literature summary extracted from

  • Chowdhury, S.F.; Joseph, L.; Kumar, S.; Tulsidas, S.R.; Bhat, S.; Ziomek, E.; Menard, R.; Sivaraman, J.; Purisima, E.O.
    Exploring inhibitor binding at the S subsites of cathepsin L (2008), J. Med. Chem., 51, 1361-1368.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.4.22.15 expressed in Pichia pastoris Homo sapiens

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
3.4.22.15 hanging drop vapour diffusion method with 17% (w/v) polyethylene glycol 8000 and 0.2 M ammonium sulfate Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.22.15 E-64
-
 Homo sapiens
3.4.22.15 ethanesulfonothioate
-
 Homo sapiens
3.4.22.15 HgCl2
-
 Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
3.4.22.15 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.22.15
-
 Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.22.15 benzyloxycarbonyl-Phe-Arg-7-amido-4-methylcoumarin + H2O
-
 Homo sapiens benzyloxycarbonyl-Phe-Arg + 7-amino-4-methylcoumarin
-
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