EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.5.1.98 | Butyrate | inhibition of histone deacetylases, results in down-regulation of HoxA9 expression | Mus musculus | |
3.5.1.98 | MS-275 | inhibition of histone deacetylases, results in down-regulation of HoxA9 expression | Mus musculus | |
3.5.1.98 | trichostatin A | inhibition of histone deacetylases, results in down-regulation of HoxA9 expression | Mus musculus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.5.1.98 | additional information | Mus musculus | histone deacetylases regulate the expression of HoxA9, which acts as a master switch to regulate the expression of prototypical endothelial-committed genes such as endothelial nitric oxide synthase, VE-cadherin, VEGF-R2, and mediates the shear stress-induced maturation of endothelial cells | ? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.5.1.98 | Mus musculus | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
3.5.1.98 | mononuclear cell | - |
Mus musculus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.5.1.98 | additional information | histone deacetylases regulate the expression of HoxA9, which acts as a master switch to regulate the expression of prototypical endothelial-committed genes such as endothelial nitric oxide synthase, VE-cadherin, VEGF-R2, and mediates the shear stress-induced maturation of endothelial cells | Mus musculus | ? | - |
? |