EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
3.2.1.17 | Protein disulfide isomerase | enhances activity of the activity of renatured lysozyme | Gallus gallus |
EC Number | Cloned (Comment) | Organism |
---|---|---|
5.3.4.1 | overexpression in Bacillus brevis, secretion to the cell medium | Humicola insolens |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
5.3.4.1 | additional information | - |
additional information | refolding reaction obeys almost first-order kinetics with respect to PDI concentration | Humicola insolens |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.2.1.17 | Gallus gallus | - |
- |
- |
5.3.4.1 | Humicola insolens | - |
- |
- |
EC Number | Renatured (Comment) | Organism |
---|---|---|
3.2.1.17 | the refolding rate increases with an increase in concentration of protein disulfide isomerase. About 100% activity is recovered after 10 min initiation of the reaction at 0.062 mM protein disulfide isomerase, whereas several hours are needed for 100% activity recovery in absence of protein disulfide isomerase | Gallus gallus |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
3.2.1.17 | egg white | - |
Gallus gallus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
5.3.4.1 | denatured lysozyme | PDI catalyzes the formation, rearrangement, and breakage of disulfide bonds, oxidative refolding by PDI almost completely restores lysozyme activity, overview | Humicola insolens | ? | - |
? | |
5.3.4.1 | additional information | PDI also functions as a dehydroascorbate reductase and a molecular chaperone besides its disulfide-isomerizing function | Humicola insolens | ? | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
5.3.4.1 | PDI | - |
Humicola insolens |
5.3.4.1 | protein disulfide isomerase | - |
Humicola insolens |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
5.3.4.1 | 22 | - |
assay at room temprature | Humicola insolens |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
5.3.4.1 | GSH | - |
Humicola insolens | |
5.3.4.1 | GSSG | - |
Humicola insolens |