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Literature summary extracted from

  • Shaw, G.C.; Kao, H.S.; Chiou, C.Y.
    Cloning, expression, and catabolite repression of a gene encoding beta-galactosidase of Bacillus megaterium ATCC 14581 (1998), J. Bacteriol., 180, 4734-4738.
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.2.1.23 additional information the enzyme expression is highly induced by lactose but not by isopropyl-beta-D-thiogalactopyranoside, IPTG Priestia megaterium

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.2.1.23 gene mbgA, DNA and amino acid sequence determination and anaylsis, genetic organization, a 27-bp inverted repeat overlaps the mbgA promoter sequence, and is a target for catabolite repressors, expression in Escherichia coli strain JM109 Priestia megaterium

Protein Variants

EC Number Protein Variants Comment Organism
3.2.1.23 additional information disruption of gene mbgA in the bacterial chromosome results in loss of lactose-inducible beta-galactosidase production, base substitutions within two partially overlapping catabolite-responsive elements CRE-I and/or CRE-II cause partial relief from catabolite repression Priestia megaterium

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.2.1.23 additional information the enzyme is subject to catabolite repression by D-glucose Priestia megaterium

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.2.1.23 118088
-
 x * 118088, sequence calculation Priestia megaterium

Organism

EC Number Organism UniProt Comment Textmining
3.2.1.23 Priestia megaterium O85167 strain ATCC 14581, gene mbgA
-

Subunits

EC Number Subunits Comment Organism
3.2.1.23 ? x * 118088, sequence calculation Priestia megaterium