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Literature summary extracted from

  • Centeno, J.M.; Burguete, M.C.; Castello-Ruiz, M.; Enrique, M.; Valles, S.; Salom, J.B.; Torregrosa, G.; Marcos, J.F.; Alborch, E.; Manzanares, P.
    Lactoferricin-related peptides with inhibitory effects on ACE-dependent vasoconstriction (2006), J. Agric. Food Chem., 54, 5323-5329.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.15.1 Ac-FKCRRWQWRMKKLGA-NH2 0.02 mM, 38% loss of activity with hippuryl-His-Leu, 41% loss of activity with angiotensin I Sus scrofa
3.4.15.1 Ac-RKKPFW-NH2 0.02 mM, 24% loss of activity with hippuryl-His-Leu Sus scrofa
3.4.15.1 Ac-RKWHFW-NH2 0.02 mM, 42% loss of activity with hippuryl-His-Leu, 55% loss of activity with angiotensin I; 0.02 mM, 48% loss of activity with hippuryl-His-Leu Sus scrofa
3.4.15.1 Ac-RKWLFW-NH2 0.02 mM, 26% loss of activity with hippuryl-His-Leu, 71% loss of activity with angiotensin I; 0.02 mM, 32% loss of activity with hippuryl-His-Leu Sus scrofa
3.4.15.1 Ac-RKWRFW-NH2 0.02 mM, 3% loss of activity with hippuryl-His-Leu Sus scrofa
3.4.15.1 Ac-RRWQWR-NH2 0.02 mM, 29% loss of activity with hippuryl-His-Leu, 34% loss of activity with angiotensin I Sus scrofa

Organism

EC Number Organism UniProt Comment Textmining
3.4.15.1 Sus scrofa
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.15.1 kidney
-
Sus scrofa
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.15.1 angiotensin I + H2O
-
Sus scrofa angiotensin II + His-Leu
-
?
3.4.15.1 hippuryl-His-Leu + H2O
-
Sus scrofa hippuric acid + His-Leu
-
?