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Literature summary extracted from

  • Jo, J.Y.; Gonzalez de Mejia, E.; Lila, M.A.
    Catalytic inhibition of human DNA topoisomerase II by interactions of grape cell culture polyphenols (2006), J. Agric. Food Chem., 54, 2083-2087.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
5.6.2.2 epicatechin gallate
-
Homo sapiens
5.6.2.2 myricetin potentiating interaction between inhibitors myricetin and resveratrol Homo sapiens
5.6.2.2 procyanidin B2 potentiating interactions between procyanidin B2 and epicatechin gallate, myricetin and resveratrol Homo sapiens
5.6.2.2 resveratrol potentiating interaction between inhibitors myricetin and resveratrol Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
5.6.2.2 Homo sapiens
-
-
-

IC50 Value

EC Number IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
5.6.2.2 0.000029
-
pH 8.0, 37°C Homo sapiens epicatechin gallate
5.6.2.2 0.000039
-
pH 8.0, 37°C Homo sapiens myricetin
5.6.2.2 0.0045
-
pH 8.0, 37°C Homo sapiens procyanidin B2
5.6.2.2 0.0657
-
pH 8.0, 37°C Homo sapiens resveratrol