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Literature summary extracted from

  • Hagiwara, H.; Tajika, Y.; Matsuzaki, T.; Suzuki, T.; Aoki, T.; Takata, K.
    Localization of Golgi 58K protein (formiminotransferase cyclodeaminase) to the centrosome (2006), Histochem. Cell Biol., 126, 251-259.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.1.2.5 centrosome more abundantly around the mother centriole. The centrosome localization of FTCD continues throughout the cell cycle and is not disrupted after Golgi fragmentation, which is induced by colcemid and brefeldin A. FTCD in the centrosome may be associated with polyglutamylated residues of centriole microtubules and may play a role in providing centrioles with glutamate produced by cyclodeaminase domains of FTCD Homo sapiens 5813
-
2.1.2.5 Golgi apparatus
-
Homo sapiens 5794
-
4.3.1.4 centrosome
-
Homo sapiens 5813
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.1.2.5 tetrahydrofolate + N-formimidoyl-L-glutamate Homo sapiens FTCD in the centrosome may be associated with polyglutamylated residues of centriole microtubules and may play a role in providing centrioles with glutamate produced by cyclodeaminase domains of FTCD 5-formimidoyltetrahydrofolate + L-glutamate
-
?
4.3.1.4 5-formimidoyltetrahydrofolate Homo sapiens
-
5,10-methenyltetrahydrofolate + NH3
-
?

Organism

EC Number Organism UniProt Comment Textmining
2.1.2.5 Homo sapiens O05954
-
-
4.3.1.4 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.1.2.5 oviduct
-
Homo sapiens
-
4.3.1.4 BALB/c 3T3 cell
-
Homo sapiens
-
4.3.1.4 HeLa cell
-
Homo sapiens
-
4.3.1.4 HSC-4 cell
-
Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.1.2.5 tetrahydrofolate + N-formimidoyl-L-glutamate
-
Homo sapiens 5-formimidoyltetrahydrofolate + L-glutamate
-
?
2.1.2.5 tetrahydrofolate + N-formimidoyl-L-glutamate FTCD in the centrosome may be associated with polyglutamylated residues of centriole microtubules and may play a role in providing centrioles with glutamate produced by cyclodeaminase domains of FTCD Homo sapiens 5-formimidoyltetrahydrofolate + L-glutamate
-
?
4.3.1.4 5-formimidoyltetrahydrofolate
-
Homo sapiens 5,10-methenyltetrahydrofolate + NH3
-
?

Synonyms

EC Number Synonyms Comment Organism
2.1.2.5 formiminotransferase cyclodeaminase
-
Homo sapiens
2.1.2.5 FTCD
-
Homo sapiens
4.3.1.4 58K Golgi protein
-
Homo sapiens
4.3.1.4 formimidoyltetrahydrofolate cyclodeaminase
-
Homo sapiens
4.3.1.4 formiminotransferase cyclodeaminase
-
Homo sapiens
4.3.1.4 FTCD
-
Homo sapiens