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Literature summary extracted from

  • Elased, K.M.; Cunha, T.S.; Marcondes, F.K.; Morris, M.
    Brain angiotensin-converting enzymes: role of angiotensin-converting enzyme 2 in processing angiotensin II in mice (2008), Exp. Physiol., 93, 665-675.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.17.23 DX600 0.01 mM, 99% inhibition Mus musculus
3.4.17.23 EDTA complete inhibition at 10 mM Mus musculus
3.4.17.23 additional information not inhibited by captopril and benzyloxycarbonyl-Pro-Pro Mus musculus

Organism

EC Number Organism UniProt Comment Textmining
3.4.17.23 Mus musculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.17.23 blood plasma
-
 Mus musculus
-
3.4.17.23 brain
-
 Mus musculus
-
3.4.17.23 brain stem
-
 Mus musculus
-
3.4.17.23 cerebral cortex
-
 Mus musculus
-
3.4.17.23 hippocampus
-
 Mus musculus
-
3.4.17.23 hypothalamus brain ACE2 activity is highest in hypothalamus Mus musculus
-
3.4.17.23 kidney
-
 Mus musculus
-
3.4.17.23 pituitary gland
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.17.23 angiotensin II + H2O
-
 Mus musculus angiotensin-(1-7) + Phe
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.17.23 ACE2
-
 Mus musculus
3.4.17.23 angiotensin converting enzyme 2
-
 Mus musculus