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Literature summary extracted from
- The discovery of angiotensin-converting enzyme 2 and its role in acute lung injury in mice (2008), Exp. Physiol., 93, 543-548.
Application
| EC Number | Application | Comment | Organism |
|---|---|---|---|
| 3.4.17.23 | medicine | ACE2 protects murine lungs from acute respiratory distress syndrome | Mus musculus |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.17.23 | additional information | the Spike protein of the SARS-coronavirus reduces ACE2 expression | Mus musculus |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.17.23 | Mus musculus | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.4.17.23 | lung | - |
Mus musculus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.17.23 | angiotensin II + H2O | - |
Mus musculus | angiotensin-(1-7) + Phe | - |
? |  |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.4.17.23 | ACE2 | - |
Mus musculus |
| 3.4.17.23 | angiotensin converting enzyme 2 | - |
Mus musculus |
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Release 2023.1 (January 2023)
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