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Literature summary extracted from

  • Fernandes, J.; Amorim, R.; Azevedo, I.; Martins, M.J.
    In vitro modulation of alkaline phosphatase activity of Saccharomyces cerevisiae grown in low or high phosphate medium (2008), Braz. J. Med. Biol. Res., 41, 41-46.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.1.3.1 beta-estradiol concentration dependent activation of alkaline phosphatase grown in low phosphate medium Saccharomyces cerevisiae
3.1.3.1 cholesterol concentration dependent activation of alkaline phosphatase grown in low phosphate medium Saccharomyces cerevisiae
3.1.3.1 L-homoarginine 5 mM, activation of alkaline phosphatase grown in high phosphate medium to 186% of the control value, alkaline phosphatase grown in low phosphate medium is activated to 166% of control Saccharomyces cerevisiae
3.1.3.1 L-Leu 5 mM, activation of alkaline phosphatase grown in high phosphate medium to 155% of the control value Saccharomyces cerevisiae
3.1.3.1 L-Phe 5 mM, activation of alkaline phosphatase grown in high phosphate medium to 168% of the control value Saccharomyces cerevisiae
3.1.3.1 levamisole 1 mM, activation of alkaline phosphatase grown in high phosphate medium to 122% of the control value Saccharomyces cerevisiae
3.1.3.1 progesterone concentration dependent activation of alkaline phosphatase grown in low phosphate medium Saccharomyces cerevisiae

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.3.1 corticosterone 5 mM, 90% inhibition of alkaline phosphatase grown in high phosphate medium, no effect is observed with alkaline phosphatase grown in low phosphate medium Saccharomyces cerevisiae
3.1.3.1 vanadate 1 mM, 22% inhibition of alkaline phosphatase grown in high phosphate medium Saccharomyces cerevisiae

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.3.1 additional information Saccharomyces cerevisiae the product of the PHO8 gene is repressible by phosphate in the medium ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.3.1 Saccharomyces cerevisiae
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.3.1 additional information the product of the PHO8 gene is repressible by phosphate in the medium Saccharomyces cerevisiae ?
-
 ?
3.1.3.1 p-nitrophenyl phosphate + H2O
-
 Saccharomyces cerevisiae p-nitrophenol + phosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.1.3.1 PHO13
-
 Saccharomyces cerevisiae
3.1.3.1 PHO8
-
 Saccharomyces cerevisiae