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Literature summary extracted from

  • Song, F.; Zhuang, Z.; Dunaway-Mariano, D.
    Structure-activity analysis of base and enzyme-catalyzed 4-hydroxybenzoyl coenzyme A hydrolysis (2007), Bioorg. Chem., 35, 1-10.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.1.2.23 0.006
-
 4-hydroxybenzoyl-CoA pH 7.5, 25°C Pseudomonas sp.
3.1.2.23 5 20 4-fluorobenzoyl-CoA pH 7.5, 25°C Pseudomonas sp.
3.1.2.23 56
-
 4-methoxybenzoyl-CoA pH 7.5, 25°C Pseudomonas sp.
3.1.2.23 230
-
 4-methylbenzoyl-CoA pH 7.5, 25°C Pseudomonas sp.
3.1.2.23 300
-
 4-trifluoromethylbenzoyl-CoA pH 7.5, 25°C Pseudomonas sp.
3.1.2.23 510
-
 benzoyl-CoA pH 7.5, 25°C Pseudomonas sp.
3.1.2.23 550
-
 4-chlorobenzoyl-CoA pH 7.5, 25°C Pseudomonas sp.

Organism

EC Number Organism UniProt Comment Textmining
3.1.2.23 Pseudomonas sp. P56653 CBS3, recombinantly expressed in Escherichia coli
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.2.23 4-Chlorobenzoyl-CoA + H2O
-
 Pseudomonas sp. 4-Chlorobenzoate + CoA
-
 ?
3.1.2.23 4-fluorobenzoyl-CoA + H2O
-
 Pseudomonas sp. 4-fluorobenzoate + CoA
-
 ?
3.1.2.23 4-Hydroxybenzoyl-CoA + H2O
-
 Pseudomonas sp. 4-Hydroxybenzoate + CoA
-
 ?
3.1.2.23 4-methoxybenzoyl-CoA + H2O
-
 Pseudomonas sp. 4-methoxybenzoate + CoA
-
 ?
3.1.2.23 4-methylbenzoyl-CoA + H2O
-
 Pseudomonas sp. 4-methylbenzoate + CoA
-
 ?
3.1.2.23 4-trifluoromethylbenzoyl-CoA + H2O
-
 Pseudomonas sp. 4-trifluoromethylbenzoate + CoA
-
 ?
3.1.2.23 Benzoyl-CoA + H2O
-
 Pseudomonas sp. Benzoate + CoA
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.1.2.23 4-HBA-CoA thioesterase
-
 Pseudomonas sp.
3.1.2.23 4-hydroxybenzoyl coenzyme A thioesterase
-
 Pseudomonas sp.

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
3.1.2.23 0.038
-
 4-trifluoromethylbenzoyl-CoA pH 7.5, 25°C Pseudomonas sp.
3.1.2.23 0.047
-
 4-methylbenzoyl-CoA pH 7.5, 25°C Pseudomonas sp.
3.1.2.23 0.27
-
 4-methoxybenzoyl-CoA pH 7.5, 25°C Pseudomonas sp.
3.1.2.23 1
-
 benzoyl-CoA pH 7.5, 25°C Pseudomonas sp.
3.1.2.23 1.1
-
 4-chlorobenzoyl-CoA pH 7.5, 25°C Pseudomonas sp.
3.1.2.23 9.7
-
 4-fluorobenzoyl-CoA pH 7.5, 25°C Pseudomonas sp.
3.1.2.23 18.3
-
 4-hydroxybenzoyl-CoA pH 7.5, 25°C Pseudomonas sp.