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Literature summary extracted from

  • Spyrakis, F.; Raboni, S.; Cozzini, P.; Bettati, S.; Mozzarelli, A.
    Allosteric communication between alpha and beta subunits of tryptophan synthase: Modelling the open-closed transition of the alpha subunit (2006), Biochim. Biophys. Acta, 1764, 1102-1109.
    View publication on PubMed

Protein Variants

EC Number Protein Variants Comment Organism
4.2.1.20 G181A 2fold decrease of activity compared to the wild type enzyme Salmonella enterica subsp. enterica serovar Typhimurium
4.2.1.20 G181F mutant shows a significant change in the alphaloop6 structure Salmonella enterica subsp. enterica serovar Typhimurium
4.2.1.20 G181P mutant shows a significant change in the alphaloop6 structure Salmonella enterica subsp. enterica serovar Typhimurium
4.2.1.20 G181V mutant shows a significant change in the alphaloop6 structure Salmonella enterica subsp. enterica serovar Typhimurium

Organism

EC Number Organism UniProt Comment Textmining
4.2.1.20 Salmonella enterica subsp. enterica serovar Typhimurium
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.2.1.20 L-serine + indole
-
 Salmonella enterica subsp. enterica serovar Typhimurium L-tryptophan + H2O
-
 ?

Synonyms

EC Number Synonyms Comment Organism
4.2.1.20 TRPS
-
 Salmonella enterica subsp. enterica serovar Typhimurium

Cofactor

EC Number Cofactor Comment Organism Structure
4.2.1.20 pyridoxal 5'-phosphate
-
 Salmonella enterica subsp. enterica serovar Typhimurium