Literature summary extracted from

Dai, J.; Wang, L.; Allen, K.N.; Radstrom, P.; Dunaway-Mariano, D.
Conformational cycling in beta-phosphoglucomutase catalysis: reorientation of the beta-D-glucose 1,6-(bis)phosphate intermediate (2006), Biochemistry, 45, 7818-7824.

Activating Compound

EC Number	Activating Compound	Comment	Organism	Structure
5.4.2.6	beta-D-glucose 1,6-bisphosphate	required, Km value 0.0065 mM. Beta-D-glucose 1,6-bisphosphate is a reaction intermediate	Lactococcus lactis

KM Value [mM]

EC Number	KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
5.4.2.6	0.049	-	beta-D-glucose 1-phosphate	pH 7.0, 25°C	Lactococcus lactis

Organism

EC Number	Organism	UniProt	Comment	Textmining
5.4.2.6	Lactococcus lactis	-	-	-

Reaction

EC Number	Reaction	Comment	Organism	Reaction ID
5.4.2.6	beta-D-Glucose 1-phosphate = beta-D-glucose 6-phosphate	phosphoryl transfer rather than ligand binding is rate-limiting. Beta-D-glucose 1,6-bisphosphate is a reaction intermediate and binds to the active site in two different orientations with roughly the same efficiency. Reorientation of the beta-D-glucose 1,6-bisphosphate intermediate occurs by diffusion into solvent followed by binding in the opposite orientation	Lactococcus lactis	a

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
5.4.2.6	beta-D-Glucose 1-phosphate	-	Lactococcus lactis	beta-D-Glucose 6-phosphate	-	?

Turnover Number [1/s]

EC Number	Turnover Number Minimum [1/s]	Turnover Number Maximum [1/s]	Substrate	Comment	Organism	Structure
5.4.2.6	177	-	beta-D-glucose 1-phosphate	pH 7.0, 25°C	Lactococcus lactis

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Release 2023.1 (January 2023)