EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.4.16.4 | 4-chloromercuribenzoate | complete inhibition at 1 mM | Priestia megaterium | |
3.4.16.4 | benzylpenicillin | 80% inhibition at 0.1 mg/ml | Priestia megaterium | |
3.4.16.4 | cefmetazole | - |
Priestia megaterium | |
3.4.16.4 | Methicillin | - |
Priestia megaterium | |
3.4.16.4 | nocardicin A | - |
Priestia megaterium | |
3.4.16.4 | penicillin | the enzyme is sensitive to inhibition, penicillin-binding profile during development of spores, overview | Priestia megaterium |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
3.4.16.4 | Mg2+ | required | Priestia megaterium |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.4.16.4 | UDP-MurNAc-L-Ala-D-Glu-L-Lys-D-Ala-D-Ala + H2O | Priestia megaterium | i.e. UDP-N-acetylmuraminoyl-pentapeptide, release of D-alanine from UDPMurNAc-pentapeptide substrate | D-Ala + UDP-MurNAc-L-Ala-D-Glu-L-Lys-D-Ala | - |
? | |
3.4.16.4 | UDP-MurNAc-L-Ala-D-Glu-L-Lys-D-Ala-D-Ala + H2O | Priestia megaterium KM / ATCC 13632 | i.e. UDP-N-acetylmuraminoyl-pentapeptide, release of D-alanine from UDPMurNAc-pentapeptide substrate | D-Ala + UDP-MurNAc-L-Ala-D-Glu-L-Lys-D-Ala | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.4.16.4 | Priestia megaterium | - |
two isozymes penicillin-binding protein 5 and penicillin-binding protein 5a | - |
3.4.16.4 | Priestia megaterium KM / ATCC 13632 | - |
two isozymes penicillin-binding protein 5 and penicillin-binding protein 5a | - |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
3.4.16.4 | additional information | during endospore development in Bacillus megaterium strain KM, unique sporulation-specific penicillin-binding proteins are synthesized and inserted into the forespore membranes, vegetative and stage-V forespore membrane DD-carboxypeptidase, penicillin-binding profile, overview | Priestia megaterium | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.4.16.4 | UDP-MurNAc-L-Ala-D-Glu-L-Lys-D-Ala-D-Ala + H2O | i.e. UDP-N-acetylmuraminoyl-pentapeptide, release of D-alanine from UDPMurNAc-pentapeptide substrate | Priestia megaterium | D-Ala + UDP-MurNAc-L-Ala-D-Glu-L-Lys-D-Ala | - |
? | |
3.4.16.4 | UDP-MurNAc-L-Ala-D-Glu-L-Lys-D-Ala-D-Ala + H2O | i.e. UDP-N-acetylmuraminoyl-pentapeptide, release of D-alanine from UDPMurNAc-pentapeptide substrate | Priestia megaterium KM / ATCC 13632 | D-Ala + UDP-MurNAc-L-Ala-D-Glu-L-Lys-D-Ala | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
3.4.16.4 | More | enzyme peptide mapping | Priestia megaterium |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
3.4.16.4 | DD-Carboxypeptidase | - |
Priestia megaterium |
3.4.16.4 | penicillin-binding protein 5 | - |
Priestia megaterium |
3.4.16.4 | penicillin-binding protein 5a | - |
Priestia megaterium |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
3.4.16.4 | 37 | - |
assay at | Priestia megaterium |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
3.4.16.4 | 5.4 | - |
vegetative and stage-V forespore membrane DD-carboxypeptidase | Priestia megaterium |